Evidence map›Paper›PMID 40281428›Full record

Observational studyBMC ophthalmology2025

Axial elongation and the spatial distribution of white and dark without pressure in myopic eyes: insights from ultra-widefield imaging.

Szy Yann Chan, Chung Ting Pan, Hai Ping Li, Yue Guo Chen

Abstract readObservational Study
In one paragraph

Observational study in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Szy Yann Chan *Department of Ophthalmology, Peking University, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Rd, Haidian District, Beijing, 100191, China.
Chung Ting Pan *Department of Ophthalmology, Peking University International Hospital, Beijing, China.
Hai Ping LiDepartment of Ophthalmology, Peking University, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Rd, Haidian District, Beijing, 100191, China.
Yue Guo ChenDepartment of Ophthalmology, Peking University, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Rd, Haidian District, Beijing, 100191, China. chenyueguo@263.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo explore the spatial distribution and associated factors of White and Dark Without Pressure lesions in myopic patients using ultra-widefield fundus imaging.

methodsThis retrospective, observational study evaluated 2,940 eyes from 1,470 patients who underwent refractive surgery. Ultra-widefield fundus imaging was used to identify and map the distribution of white and dark without pressure lesions across 12 retinal sectors. Correlations between the incidence of these lesions, their location, axial length, and the number of affected sectors were analyzed.

resultsWhite and dark without pressure lesions were present in 907 eyes (30.8%), with a significant association between increased axial length and higher incidence of white and dark without pressure (P < 0.001). Lesions were predominantly located in the temporal retina, specifically in the inferotemporal and superotemporal sectors. Longer axial length and younger age were both associated with a higher number of affected sectors and a more posterior localization of lesions.

conclusionAxial elongation is significantly correlated with both the occurrence and posterior localization of white and dark without pressure lesions, as well as a higher number of affected sectors in myopic eyes. Ultra-widefield fundus imaging offers a comprehensive perspective on these retinal changes, providing valuable insights into the pathophysiology of white and dark without pressure.

Indexed as

Axial Length, EyeMyopiaRetinaAdultAgedFemaleFundus OculiHumansIntraocular PressureMaleMiddle AgedRetrospective StudiesTomography, Optical CoherenceYoung AdultDark without pressureDWOPUltra-widefield fundus imageWhite without pressureWWOP

Identifiers

PMID40281428
PMCPMC12023446

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.