Evidence map›Paper›PMID 40281276›Full record

ArticleJournal of general internal medicine2025

Inequities in Opioid Administration by Race and Ethnicity for Hospitalized Patients With and Without Substance Use Disorders.

Aksharananda Rambachan, Margaret C Fang

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Aksharananda RambachanDivision of Hospital Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA. aksharananda.rambachan@ucsf.edu.ORCID 0000-0002-8506-5086
Margaret C FangDivision of Hospital Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.

Funding

Use and outcomes of anticoagulants for the treatment and prevention of thrombosis among hospitalized patientsK24HL141354 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FANG, MARGARET C. · 2018 to 2022
$731k
NHLBI Division of Intramural Research K24HL141354NHLBI NIH HHS K24 HL141354UCSF PARC Fellowship
6 · The paper itself

Abstract

backgroundAdequate pain management is challenging in patients with substance use disorders, particularly those from racial/ethnic minority groups who face intersecting biases.

objectiveTo investigate inequities in pain management for racial/ethnic minority groups with and without concurrent substance use disorders.

designRetrospective cohort study from 2021 to 2022 on an acute care general medicine service at UCSF Medical Center.

participantsAll adults ≥ 18 years old. EXPOSURES: Primary exposure was the patient's self-identified race/ethnicity (Asian, Black or African American, Latino, Multi-Race/Ethnicity, Native American or Alaska Native, Native Hawaiian or Pacific Islander, Southwest Asian or North African, White, Other, and Unknown/Declined). MAIN OUTCOME AND MEASURES: The primary outcome was average daily inpatient opioids received (morphine milligram equivalents, MME). Multivariable negative binomial regression assessed the relationship between self-reported race/ethnicity and opioid administration, adjusting for demographics, clinical factors, substance use disorders, and pain characteristics. The subgroup analyses focused on patients with substance use disorders and on patients without any buprenorphine or methadone prescriptions. KEY

resultsIn the overall cohort of 13,058 hospitalizations (mean age 62.7 years, 51.2% male, 31.3% with substance use disorder), patients from racial/ethnic minority groups received significantly fewer opioids than White patients in adjusted analyses: Asian (- 61.3 MME/day), Black (- 44.9 MME/day), Latino (- 48.8 MME/day), Native American/Alaska Native (- 80.4 MME/day), and Native Hawaiian/Pacific Islander (- 72.9 MME/day). Similar, significant disparities were present in both subgroups. Notably, in the substance use disorder-only subgroup (n = 4446), larger disparities persisted for Asian (- 124.4 MME/day), Black (- 68.7 MME/day), and Latino (- 110.8 MME/day) patients compared to White patients.

conclusionsSubstantial racial/ethnic inequities in inpatient opioid prescribing for pain control were observed, particularly among patients with concurrent substance use disorders. These findings highlight the need for interventions promoting equitable, culturally competent pain management for marginalized populations facing intersecting biases and stigma.

Indexed as

Analgesics, OpioidEthnicityHealthcare DisparitiesPain ManagementRacial GroupsSubstance-Related DisordersAdultAgedCohort StudiesFemaleHospitalizationHumansMaleMiddle AgedRetrospective StudiesAnalgesics, OpioidHealth equityHospital medicinePain managementSubstance use disorders

Identifiers

PMID40281276
PMCPMC12463787

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.