Evidence map›Paper›PMID 40281211›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2025

Blood pressure control, hypertension phenotypes, and albuminuria: outcomes of the comprehensive Basel Postpartum Hypertension Registry.

Leana N Hotz, Thilo Burkard, Alessandro Rana, Celine A Wenker, Subeedhja Jalanthiran, Leana Piattini, Noémie Strobel, Viviane Vorster, Zoë G Menzinger, Sophia Eichler and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Leana N Hotz *Medical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Thilo Burkard *Medical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Alessandro RanaMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Celine A WenkerMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Subeedhja JalanthiranMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Leana PiattiniMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Noémie StrobelMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Viviane VorsterMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Zoë G MenzingerMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Sophia EichlerMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Christina SchumacherMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Michael MayrMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Michael DickenmannDepartment of Nephrology, University Hospital Basel, Basel, Switzerland.
Irene HoesliDepartment of Obstetrics and Gynecology, University Hospital Basel, Basel, Switzerland.
Olav LapaireDepartment of Obstetrics and Gynecology, University Hospital Basel, Basel, Switzerland.
Beatrice MosimannDepartment of Obstetrics and Gynecology, University Hospital Basel, Basel, Switzerland.
Annina S VischerMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.
Thenral SocratesMedical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland. thenral.socrates@usb.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postpartum hypertension (PPHT) affects 20% of pregnancies and is strongly correlated to cardiovascular and kidney disease. Most outcome data stems from preeclampsia (PE) neglecting other hypertensive disorders of pregnancy (HDP). This analysis aimed to investigate blood pressure (BP) control, BP phenotypes, therapeutic intensity scores (TIS), and albuminuria across the spectrum of PPHT in the short-medium term.This analysis prospectively followed 370 cases of PPHT. Automated office BP measurements (AOBPM), 24-hour ambulatory BP measurements (24ABPM), TIS and Kidney Disease Improving Global Outcomes (KDIGO) > A2 levels of albumin to creatinine ratio (ACR) were measured at 3 (V3) and 12 (V12) months postpartum. Outcomes were percentage of participants with non-hypertensive AOBPM and awake 24ABPM, whitecoat, and masked hypertension, and an A2 ACR at V3 and V12. The Basel-PPHT cohort consisted of 11.9% (n = 44) chronic hypertension, 31.9% (n = 118) gestational hypertension, 55.4% (n = 205) PE, eclampsia or HELLP, and 18.4% (n = 68) de novo PPHT. Antihypertensive medication was prescribed at baseline, V3 and V12 in 85.4% (n = 316), 19.2% (n = 46), and 20% (n = 21). At V12, 9.3% (n = 5) with PE, eclampsia, and HELLP vs 31.4% (n = 16) of the remaining cohort required antihypertensive medication, p = 0.005. Non-hypertensive BP without medication was seen at V3 and V12 in 47.9% (n = 103) and 62.4% (n = 63), respectively. Albuminuria at baseline, V3 and V12 was 84.9% (n = 124), 29.9% (n = 63), and 16.9% (n = 14) respectively. The Basel-PPHT registry identified undertreatment and persistent albuminuria, despite structured management. Importantly, those without preeclampsia also required stricter controls. Therefore, rigorous follow-ups are crucial for enhancing cardiovascular and renal outcomes in this population.

Indexed as

AlbuminuriaBlood PressureHypertensionPuerperal DisordersAdultAntihypertensive AgentsFemaleHumansPhenotypePostpartum PeriodPregnancyProspective StudiesRegistriesAntihypertensive AgentsBlood pressure phenotypesCardiovascular riskHypertensive disorders in pregnancyPostpartum hypertension

Identifiers

PMID40281211
PMCPMC12229887

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.