ArticleNature communications2025
Interactive symbolic regression with co-design mechanism through offline reinforcement learning.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed.
- Introduction to using symbolic regression for interpretable machine learning in healthcare.Communications medicine · 2026Review
- Article
- Moving from table to graph in physics-informed spatio-temporal symbolic regression.Scientific reports · 2026Article
- Constraint aware and uncertainty informed QSAR modeling of Tetrahymena pyriformis toxicity using physicochemical descriptors.Scientific reports · 2026Article
- Data-driven discovery of digital twins in biomedical research.Briefings in bioinformatics · 2026Review
- LogicSR: prior-guided symbolic regression for gene regulatory network inference from single-cell transcriptomics data.Briefings in bioinformatics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Symbolic Regression holds great potential for uncovering underlying mathematical and physical relationships from observed data. However, the vast combinatorial space of possible expressions poses significant challenges for previous online search methods and pre-trained transformer models, which mostly do not consider the integration of domain experts' prior knowledge. To address these challenges, we propose the Symbolic Q-network, an advanced interactive framework for large-scale symbolic regression. Unlike previous transformer-based SR approaches, Symbolic Q-network leverages reinforcement learning without relying on a transformer-based decoder. Furthermore, we propose a co-design mechanism, where the Symbolic Q-network facilitates effective interaction with domain experts at any stage of the equation discovery process. Our extensive experiments demonstrate Sym-Q performs comparably to existing pretrained models across multiple benchmarks. Furthermore, our experiments on real-world cases demonstrate that the interactive co-design mechanism significantly enhances Symbolic Q-network's performance, achieving greater performance gains than standard autoregressive models.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.