Evidence map›Paper›PMID 40280960›Full record

ArticleNature communications2025

Interactive symbolic regression with co-design mechanism through offline reinforcement learning.

Yuan Tian, Wenqi Zhou, Michele Viscione, Hao Dong, David S Kammer, Olga Fink

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuan TianInstitute for Building Materials, ETH Zürich, Zürich, Switzerland.ORCID http://orcid.org/0000-0002-4521-2096
Wenqi ZhouInstitute for Building Materials, ETH Zürich, Zürich, Switzerland.ORCID http://orcid.org/0009-0009-0948-7787
Michele ViscioneLaboratory of Intelligent Maintenance and Operations Systems, EPFL, Lausanne, Switzerland.ORCID http://orcid.org/0009-0001-4388-477X
Hao DongLaboratory of Intelligent Maintenance and Operations Systems, EPFL, Lausanne, Switzerland.ORCID http://orcid.org/0009-0000-8562-1946
David S KammerInstitute for Building Materials, ETH Zürich, Zürich, Switzerland.ORCID http://orcid.org/0000-0003-3782-9368
Olga FinkLaboratory of Intelligent Maintenance and Operations Systems, EPFL, Lausanne, Switzerland. olga.fink@epfl.ch.ORCID http://orcid.org/0000-0002-9546-1488

Funding

Hasler Stiftung (Hasler Foundation) 24019
6 · The paper itself

Abstract

Symbolic Regression holds great potential for uncovering underlying mathematical and physical relationships from observed data. However, the vast combinatorial space of possible expressions poses significant challenges for previous online search methods and pre-trained transformer models, which mostly do not consider the integration of domain experts' prior knowledge. To address these challenges, we propose the Symbolic Q-network, an advanced interactive framework for large-scale symbolic regression. Unlike previous transformer-based SR approaches, Symbolic Q-network leverages reinforcement learning without relying on a transformer-based decoder. Furthermore, we propose a co-design mechanism, where the Symbolic Q-network facilitates effective interaction with domain experts at any stage of the equation discovery process. Our extensive experiments demonstrate Sym-Q performs comparably to existing pretrained models across multiple benchmarks. Furthermore, our experiments on real-world cases demonstrate that the interactive co-design mechanism significantly enhances Symbolic Q-network's performance, achieving greater performance gains than standard autoregressive models.

Identifiers

PMID40280960
PMCPMC12032090

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.