ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
Ruthenium Single-Atom Nanozyme Driven Sonosensitizer with Oxygen Vacancies Enhances Electron-Hole Separation Efficacy and Remodels Tumor Microenvironment for Sonodynamic-Amplified Ferroptosis.
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Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36citing papers in PubMed
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Who cites it
36 citing papers in PubMed.
- Single-atom nanozymes in nanomedicine: catalytic precision, mechanistic insights, and translational opportunities.Chemical science · 2026Review
- Advances in ultrasound-mediated nanozyme systems in therapeutic applications.Ultrasonics sonochemistry · 2026Review
- A Solution to Nanozyme Inefficiency: Ultrasound-Enhanced and Biofilm-Targeted Catalytic Therapy for Eradicating Bacterial Infections.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Single-cell transcriptomic analysis of ferroptosis-associated cell populations in the progression of diabetic retinopathy.International ophthalmology · 2026Article
- Oxygen Vacancy-Enriched Platinum Single-Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A hemoglobin-based nanozyme with ruthenium-induced nanomotor ability exhibiting photothermal and chemodynamic responses.Mikrochimica acta · 2026Article
- Silicon doping-engineered asymmetric coordination and electronic structure modulation for amplified single-atom nanozyme catalytic therapy.Materials today. Bio · 2026Article
- Global research trends and emerging frontiers of nanozymes in cancer therapy based on bibliometric and knowledge mapping analysis from 2001 to 2025.Discover nano · 2026Review
- A Natural product-based composite nanozyme synergistically induces ferroptosis for lung cancer therapy.RSC advances · 2026Article
- Augmenting the catalytic activity of ADzymes: strategic engineering from atomic structure design to macro-environmental interaction for enhanced biomedical efficacy.Journal of nanobiotechnology · 2026Review
- Dual inhibition of xCT and GGCT induces ferroptosis in glioblastoma cells by depleting cysteine and disrupting redox homeostasis.Cell death discovery · 2026Article
- Iron single-atom nanozyme-mediated laser interstitial thermal therapy and anti-inflammatory effect for epilepsy.Materials today. Bio · 2026Article
- Inflammation-targeted single-atom nanozymes drive microglial depolarization and inhibit ferroptosis via Sirt-6-xCT-GPX4 axis to attenuate early brain injury following subarachnoid hemorrhage.Materials today. Bio · 2026Article
- Microglial Membranes Wrapped Ultrasmall Medium-Entropy Ru Single-Atom Nanozyme: Enhanced Catalysis for Accelerating Inflammation/Redox Microenvironment Regulation in Intracerebral Hemorrhage.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Nanobiotechnology-driven advances in sonodynamic therapy: unlocking the potential of sonosensitizers in clinical translation.RSC advances · 2026Review
- Nanozymes in Tumor Microenvironment Modulation for Cancer Therapy.Biomaterials research · 2026Review
- Pharmacologically inherited carbon dots fromTheranostics · 2026Article
- LINC-EPS Protects Against Neurodegeneration by Driving a PGC-1α-Mediated Anti-Ferroptosis Program in Parkinson's Disease.International journal of biological sciences · 2026Article
- From Barrier to Gateway: Nanomaterials Reshaping the Tumor Microenvironment for Therapy.International journal of nanomedicine · 2026Review
- Nano-Enabled Fluorescence Switching: A Novel Strategy for PDGFRβ Detection and TKI Therapy Monitoring.Research (Washington, D.C.) · 2026Article
Corrections and comments
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Authors and funding
15 authors.
Yang ZhuDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.ORCID https://orcid.org/0000-0002-4747-9130
Dengliang WangDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.
Chengzhong DuDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.
Tiantian WuSchool of Pharmaceutical Sciences/NHC key laboratory of tropical disease control/School of Tropical Medicine, Hainan Medical University, Haikou, 571199, P. R. China.
Penghui WeiDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.
Hongjia ZhengDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.
Guanting LiDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.
ShunZhe ZhengDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.
Lichao SuDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.
Lingjun YanDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.
Yongrui HuDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.
Huimin WangDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.
Lisen LinDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.ORCID https://orcid.org/0000-0003-4060-8881
Chenyu DingDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350209, P. R. China.
Xiaoyuan ChenDepartments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, 119074, Singapore.ORCID https://orcid.org/0000-0002-9622-0870
Funding
Fujian Medical Innovation Project Funding Program 2024CXA016Joint Funds for the innovation of science and Technology, Fujian province 2023Y9090National Medical Research Council CG21APR1005National Medical Research Council MOH-001388-00National Medical Research Council MOH-001500-00National Medical Research Council MOH-001609-00National Natural Science Foundation of China 82273290National University of Singapore 23-0173-A0001Singapore Ministry of Education MOE-000387-00Singapore Ministry of Education MOET32023-0005
Abstract
Sonodynamic therapy (SDT) has emerged as a promising noninvasive approach for tumor therapy. However, the effectiveness of traditional inorganic semiconductor sonosensitizers is hindered by rapid electron (e
Indexed as
FerroptosisOxygenRutheniumTumor MicroenvironmentUltrasonic TherapyAnimalsCell Line, TumorHumansMiceNanoparticlesReactive Oxygen SpeciesTitaniumOxygenReactive Oxygen SpeciesRutheniumTitaniumtitanium dioxideferroptosisoxygen vacancysingle‐atom nanozymesonodynamic therapytumor microenvironment
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.