Evidence map›Paper›PMID 40279576›Full record

ArticleJournal of medical Internet research2025

The Role of Digital Opinion Leaders in Dengue Prevention Through Health Promotion and Public Health Collaboration: Qualitative Semistructured Interview Study.

Andrew Green, Shishi Wu, Alberta Di Pasquale, Tikki Pang

Abstract read
In one paragraph

Article in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew GreenRegional Medical Affairs Vaccines, Growth and Emerging Markets, Takeda Pharmaceuticals International AG Singapore Branch, Singapore, Singapore.ORCID https://orcid.org/0000-0002-6325-5970
Shishi WuIQVIA Real World Solutions Asia-Pacific, Singapore, Singapore.ORCID https://orcid.org/0009-0000-0900-097X
Alberta Di PasqualeRegional Medical Affairs Vaccines, Growth and Emerging Markets, Takeda Pharmaceuticals International AG Singapore Branch, Singapore, Singapore.ORCID https://orcid.org/0000-0002-8566-5057
Tikki PangYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID https://orcid.org/0009-0000-2481-1914

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDengue fever is a significant public health concern. The advent of social media has introduced digital opinion leaders (DOLs), health care professionals with substantial online followings who play a pivotal role in disseminating health information and combating misinformation.

objectiveWe aimed to investigate the role of DOLs in dengue prevention and explore their preferences for collaboration with health sector entities to strengthen dengue prevention initiatives.

methodsA qualitative study was conducted using semistructured interviews with 37 purposively selected DOLs from 8 countries in Latin America and Southeast Asia. They were selected based on their active online presence, dissemination of dengue-related content, and substantial social media followings. Interviews took place either in person or online, according to the participants' chosen languages. Each session, lasting approximately 60 minutes, was audio recorded, transcribed verbatim, and subjected to thematic analysis to identify recurring themes.

resultsThe thematic analysis led to several key findings. First, DOLs used social media to enhance public health communication, focusing on raising awareness (16/37, 43%), correcting misconceptions (17/37, 46%), and modeling preventive behaviors (8/37, 22%) for infectious diseases. They educated audiences on disease symptoms and prevention, addressed vaccine hesitancy, and shared personal practices to encourage similar actions among followers. Second, 35% (13/37) of the DOLs reported a widespread lack of public knowledge about dengue and its prevention, with even less awareness of vaccine availability. In addition, 27% (10/37) of them identified challenges due to antivaccination sentiments and misinformation, while 8% (3/37) noted obstacles from perceived inadequate government leadership in dengue prevention. In response, DOLs leveraged their social media influence to educate the public. A significant number (22/37, 59%) of the DOLs emphasized the importance of regular promotion of vector control measures as the cornerstone of dengue prevention and 68% (25/37) highlighted the critical role of vaccines, particularly among vulnerable groups. Finally, collaboration was essential for expanding DOLs' reach and credibility, with 54% (20/37) of them partnering with pharmaceutical companies, 43% (16/37) with government agencies, and 27% (10/37) with nongovernmental organizations. In these collaborations, 38% (14/37) of the DOLs emphasized the importance of adhering to ethical standards, and 57% (21/37) prioritized projects aligning with their personal values and professional standards, avoiding producing content that contradicted their beliefs or goals.

conclusionsDOLs are essential in disseminating dengue prevention information. They recognize their responsibility to raise awareness about dengue vaccines and dispel related misconceptions to combat vaccine hesitancy. Unlike nonmedical social media influencers, whose content may lack medical accuracy and be driven by monetization, DOLs provide evidence-based information, enhancing their credibility. Collaborations between DOLs and health sector stakeholders, although currently limited, hold significant potential for effective dengue prevention, provided they adhere to ethical standards and are supported by credible scientific evidence.

Indexed as

DengueHealth PromotionLeadershipPublic HealthSocial MediaAdultFemaleHumansInterviews as TopicLatin AmericaMaleQualitative Researchdengue preventiondigital opinion leadershealth care providerspublic health promotionsocial mediavaccine hesitancy

Identifiers

PMID40279576
PMCPMC12064970

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.