Evidence map›Paper›PMID 40279454›Full record

ArticleRevista medica del Instituto Mexicano del Seguro Social2025

[Hidradenitis suppurativa, report with dual therapy: small molecules and biological therapy].

Paola Denise Elizalde-Hernández, Andres Jhojairo Solis-González, Fabiola Leonor Méndez-Flores, Lorena Estrada-Aguilar

Abstract readCase ReportsEnglish Abstract
In one paragraph

Article in Revista medica del Instituto Mexicano del Seguro Social, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paola Denise Elizalde-HernándezInstituto Mexicano del Seguro Social, Hospital General de Zona y Medicina Familiar No. 1, Servicio de Dermatología. Chetumal, Quintana Roo, México.ORCID 0009-0008-5252-7214
Andres Jhojairo Solis-GonzálezInstituto Mexicano del Seguro Social, Hospital General de Zona y Medicina Familiar No. 1, Médico Pasante de Servicio Social. Chetumal, Quintana Roo, México.ORCID 0009-0008-5950-9086
Fabiola Leonor Méndez-FloresInstituto Mexicano del Seguro Social, Hospital General de Zona y Medicina Familiar No. 1, Servicio de Urgencias. Chetumal, Quintana Roo, México.ORCID 0009-0002-3968-7367
Lorena Estrada-AguilarInstituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Hospital Regional "Lic. Adolfo Lopez Mateos", Servicio de Dermatología. Ciudad de México, México.ORCID 0000-0002-4188-117X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hidradenitis suppurativa is an immune-mediated disease characterized by abscesses, deep nodules and fistulas that connect them to each other or connect to the surface, creating infectious processes that are difficult to control, healing of fistulas, retractable tracts and painful ulcers of slow evolution that lead the patient to depression and anxiety. Treatment still shows unsatisfactory results for patient health. Clinic case: A 27-year-old woman with a 5-year history of this pathology in Hurley stage III is presented. Because of failure to treatment with first lines of management. Anti IL-17 biologic was started, with poor response, so JAK inhibitor was added with adequate response at 4 weeks in the modified Hurley scale, VAS of pain and DLQI. Conclusion: Combined therapy mediated by cytokines and cells of the humoral response of retractile and fistulous lesions in Hurley stages II and III is proposed as an adjuvant in the chronic response of the disease.

Indexed as

Biological TherapyHidradenitis SuppurativaJanus Kinase InhibitorsAdultDrug Therapy, CombinationFemaleHumansJanus Kinase Inhibitors

Identifiers

PMID40279454
PMCPMC12052395

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.