Evidence map›Paper›PMID 40279413›Full record

ArticleScience advances2025

A wearable tool for real-time dose monitoring during cancer radiation therapies.

Ilaria Fratelli, Sara M Carturan, Francesco Tommasino, Laura Basiricò, Felix Pino, Antonio Valletta, Marcello Campajola, Matteo Rapisarda, Sabrina Calvi, Mattia Scagliotti and 14 more

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Ilaria FratelliDepartment of Physics and Astronomy, University of Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.ORCID 0000-0001-6292-0118
Sara M CarturanDepartment of Physics and Astronomy, University of Padova, Via Marzolo 8, Padova, Italy.ORCID 0000-0002-6702-2867
Francesco TommasinoDepartment of Physics, University of Trento, Via Sommarive 9, Povo, 38123 Trento, Italy.ORCID 0000-0002-8684-9261
Laura BasiricòDepartment of Physics and Astronomy, University of Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.ORCID 0000-0002-0852-1770
Felix PinoDepartment of Physics and Astronomy, University of Padova, Via Marzolo 8, Padova, Italy.
Antonio VallettaINFN, Sezione di RomaTre, Via Della Vasca Navale 84, 00146 Roma, Italy.ORCID 0000-0002-3901-9230
Marcello CampajolaINFN-Sezione di Napoli-Complesso Univ. di Monte S. Angelo, Edificio G, Via Cintia, 80126 Napoli, Italy.ORCID 0000-0003-2518-7134
Matteo RapisardaINFN, Sezione di RomaTre, Via Della Vasca Navale 84, 00146 Roma, Italy.ORCID 0000-0002-2629-3855
Sabrina CalviINFN, Sezione di RomaTre, Via Della Vasca Navale 84, 00146 Roma, Italy.ORCID 0000-0002-5099-9241
Mattia ScagliottiINFN, Sezione di RomaTre, Via Della Vasca Navale 84, 00146 Roma, Italy.ORCID 0000-0001-8505-6377
Andrea CiavattiDepartment of Physics and Astronomy, University of Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.ORCID 0000-0002-7877-7739
Luca TortoraINFN, Sezione di RomaTre, Via Della Vasca Navale 84, 00146 Roma, Italy.ORCID 0000-0003-3053-2406
Enrico VerroiTrento Institute for Fundamental Physics and Applications, Via Sommarive 9, Povo, 38123 Trento, Italy.
Jessica C DelgadoDepartment of Physics and Astronomy, University of Padova, Via Marzolo 8, Padova, Italy.ORCID 0000-0002-1017-1554
Lorenzo MargottiDepartment of Physics and Astronomy, University of Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.ORCID 0009-0005-1544-416X
Camilla BordoniDepartment of Physics and Astronomy, University of Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.ORCID 0009-0003-6564-4747
Giulia NapolitanoDepartment of Physics and Astronomy, University of Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.ORCID 0009-0009-1790-5416
Sandra MorettoDepartment of Physics and Astronomy, University of Padova, Via Marzolo 8, Padova, Italy.
Alberto AloisioINFN-Sezione di Napoli-Complesso Univ. di Monte S. Angelo, Edificio G, Via Cintia, 80126 Napoli, Italy.ORCID 0000-0002-3883-6693
Ettore SarnelliINFN-Sezione di Napoli-Complesso Univ. di Monte S. Angelo, Edificio G, Via Cintia, 80126 Napoli, Italy.ORCID 0000-0003-2739-0013
Paolo BranchiniINFN, Sezione di RomaTre, Via Della Vasca Navale 84, 00146 Roma, Italy.ORCID 0000-0002-2270-9673
Luigi MariucciINFN, Sezione di RomaTre, Via Della Vasca Navale 84, 00146 Roma, Italy.ORCID 0000-0003-1872-0009
Alberto QuarantaTrento Institute for Fundamental Physics and Applications, Via Sommarive 9, Povo, 38123 Trento, Italy.ORCID 0000-0003-1320-091X
Beatrice FraboniDepartment of Physics and Astronomy, University of Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.ORCID 0000-0002-4875-3816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on a wearable, human tissue-equivalent, real-time dosimeter designed to quantitatively monitor radiation absorbed by patients during cancer treatments. The fully organic device has been characterized under actual clinical conditions using a high-energy proton beam and an anthropomorphic phantom, with the aim to simulate a prostate cancer proton therapy treatment. We achieved a full control over the dosimeter operation, and we verified its linear response with the received dose. We demonstrate that, by a proper functionalization of the polysiloxane-based scintillator, it is possible to target the effective detection of different kinds of ionizing radiation. Specifically, besides protons, we develop a device able to detect thermal neutrons, targeting its use during Boron Neutron Capture Therapy. This work demonstrates how organic indirect detectors can be considered a universal radiation detecting platform able to monitor in real time and in situ the dose absorbed by patients during cancer treatments under different kinds of radiation.

Indexed as

NeoplasmsProstatic NeoplasmsWearable Electronic DevicesBoron Neutron Capture TherapyHumansMalePhantoms, ImagingProton TherapyRadiometryRadiotherapy Dosage

Identifiers

PMID40279413
PMCPMC12024650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.