Evidence map›Paper›PMID 40279321›Full record

ArticleThe American journal of case reports2025

Capnocytophaga canimorsus from Dog Saliva Exposure Causing Severe Sepsis in a Healthy Adult: A Case Report.

Megan A Stephens, Nawras Silin, Tahani Dakkak, Sangamithra Sathian, Aditya K Ghosh, Hardeep Singh, Navneeth Bongu

Abstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Megan A StephensGraduate Medical Education Research Department, Northeast Georgia Medical Center, Gainesville, GA, USA.
Nawras SilinDepartment of Internal Medicine, Northeast Georgia Medical Center, Gainesville, GA, USA.
Tahani DakkakGraduate Medical Education Research Department, Northeast Georgia Medical Center, Gainesville, GA, USA.
Sangamithra SathianDepartment of Internal Medicine, Northeast Georgia Medical Center, Gainesville, GA, USA.
Aditya K GhoshDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-9247-5999
Hardeep SinghGraduate Medical Education Research Department, Northeast Georgia Medical Center, Gainesville, GA, USA.ORCID 0009-0000-1545-5188
Navneeth BonguDepartment of Critical Care, Northeast Georgia Medical Center, Gainesville, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Capnocytophaga canimorsus is a gram-negative bacterium commonly found in the saliva of dogs and cats. It has the ability to evade the human immune system and cause life-threatening infections, particularly in immunocompromised individuals. C. canimorsus infection was first described in 1976, and additional cases have since been reported, with complications varying from mild to severe. This case report highlights the occurrence of a severe C. canimorsus infection in an immunocompetent patient, which rapidly progressed to septic shock and multiorgan failure. CASE REPORT We present the case of a 63-year-old man with no significant past medical history who presented with weakness, fatigue, and confusion. Further investigation revealed a wound on his lower right extremity, which had been licked by his dog. The causative pathogen was identified as C. canimorsus through blood culture and mass spectrometry. The patient experienced septic shock with multiorgan failure, including acute renal failure, liver failure, and coagulopathy. Prompt initiation of empirical broad-spectrum antibiotics prior to identification of the source of infection proved to be beneficial, resulting in clinical and symptomatic improvement for the patient. CONCLUSIONS This case emphasizes the severe complications that can arise from C. canimorsus infection in immunocompetent individuals, underscoring the importance of early recognition and treatment in cases of sepsis, particularly in those with potential dog saliva exposure.

Indexed as

CapnocytophagaGram-Negative Bacterial InfectionsSalivaSepsisShock, SepticAnimalsAnti-Bacterial AgentsDogsHumansMaleMiddle AgedMultiple Organ FailureAnti-Bacterial Agents

Identifiers

PMID40279321
PMCPMC12035970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.