Evidence map›Paper›PMID 40279262›Full record

Observational studyRevista medica del Instituto Mexicano del Seguro Social2025

[Elevated neutrophil-lymphocyte ratio and delayed graft function].

Itzy Maely Gaytán-Campos, Aurelio Chávez-Meza, José Oscar Juaréz-Sánchez, Yumar Alfredo Hurtado-Castillo, Rafael Luna-Montalbán, Martha Alicia Hernández-González

Abstract readEnglish AbstractObservational Study
In one paragraph

Observational study in Revista medica del Instituto Mexicano del Seguro Social, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. [Comment on the article "Elevated neutrophil-lymphocyte ratio and delayed graft function"].Revista medica del Instituto Mexicano del Seguro Social · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Itzy Maely Gaytán-CamposInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No.1, Servicio de Nefrología. León, Guanajuato, México.ORCID 0009-0000-5720-4774
Aurelio Chávez-MezaInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No.1, Servicio de Nefrología. León, Guanajuato, México.ORCID 0009-0009-5764-7626
José Oscar Juaréz-SánchezInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No.1, Servicio de Nefrología. León, Guanajuato, México.ORCID 0000-0002-3560-7879
Yumar Alfredo Hurtado-CastilloInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No.1, Servicio de Nefrología. León, Guanajuato, México.ORCID 0009-0007-4479-4251
Rafael Luna-MontalbánInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No.1, Servicio de Medicina Interna - Infectología. León, Guanajuato, México.ORCID 0000-0002-2411-7524
Martha Alicia Hernández-GonzálezInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No.1, División de Investigación en Salud. León, Guanajuato, México.ORCID 0000-0002-6903-2233

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Delayed graft function (DGF) is a significant complication in kidney transplantation, adversely affecting graft and recipient survival. Therefore, it is important to establish tools that help predict this condition. The elevation of the neutrophil-to-lymphocyte ratio (NLR) has been studied as a predictor of DGF, with the premise that its increase is associated with systemic inflammation and, consequently, DGF. Objective: To analyze the association between an elevated NLR in the preoperative period and delayed graft function in kidney transplant recipients. Materials and methods: A prospective, observational, analytical, and longitudinal study. The sample included all patients admitted to the Nephrology Transplant Service at Hospital de Especialidades No. 1, Centro Médico Nacional Bajío, in 2023. Results: We found that an NLR greater than 3.5 in the preoperative period of patients undergoing kidney transplantation had 80% specificity and 28% sensitivity, compared to patients with an NLR of 3.5 or lower. Conclusions: There is no association between an elevated NLR in the preoperative period and delayed kidney graft function after transplantation. However, it may be associated with other risk factors, as demonstrated in the multivariate analysis, which revealed that donor acute kidney injury increased the likelihood of developing DGF by almost 200%.

Indexed as

Delayed Graft FunctionKidney TransplantationLymphocytesNeutrophilsAdultFemaleHumansLeukocyte CountLongitudinal StudiesLymphocyte CountMaleMiddle AgedProspective StudiesRisk FactorsAcute Kidney InjuryKidney TransplantationNeutrophilsTissue Donors

Identifiers

PMID40279262
PMCPMC12048166

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.