Evidence map›Paper›PMID 40279164›Full record

ReviewThe Journal of general virology2025

Emergence, migration and spreading of the high pathogenicity avian influenza virus H5NX of the Gs/Gd lineage into America.

Alejandro J Aranda, Gabriela Aguilar-Tipacamú, Daniel R Perez, Bernardo Bañuelos-Hernandez, George Girgis, Xochitl Hernandez-Velasco, Socorro M Escorcia-Martinez, Inkar Castellanos-Huerta, Victor M Petrone-Garcia

Abstract readReview
In one paragraph

Review in The Journal of general virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alejandro J ArandaMaestría en Salud y Producción Animal Sustentable, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Querétaro, Mexico.
Gabriela Aguilar-TipacamúMaestría en Salud y Producción Animal Sustentable, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Querétaro, Mexico.
Daniel R PerezDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.
Bernardo Bañuelos-HernandezFacultad de Veterinaria, Universidad De La Salle Bajío, Avenida Universidad 602, Lomas del Campestre, León, México.
George GirgisNevysta Laboratory, Iowa State University Research Park, Ames, Lowa, USA.
Xochitl Hernandez-VelascoDepartamento de Medicina y Zootecnia de Aves, Facultad de Medicina Veterinaria y Zootecnia (FMVZ), Universidad Nacional Autónoma de México (UNAM), Cd. de México, México.
Socorro M Escorcia-MartinezDepartamento de Medicina y Zootecnia de Aves, Facultad de Medicina Veterinaria y Zootecnia (FMVZ), Universidad Nacional Autónoma de México (UNAM), Cd. de México, México.
Inkar Castellanos-HuertaDepartment of Poultry Science, University of Arkansas, Fayetteville, Arkansas, USA.
Victor M Petrone-GarciaDepartamento de Ciencias Pecuarias, Facultad de Estudios Superiores de Cuautitlán (FESC), Universidad Nacional Autónoma de México (UNAM), Cuautitlán, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high pathogenicity avian influenza virus H5N1, which first emerged in the winter of 2021, has resulted in multiple outbreaks across the American continent through the summer of 2023 and they continue based on early 2025 records, presenting significant challenges for global health and food security. The viruses causing the outbreaks belong to clade 2.3.4.4b, which are descendants of the lineage A/Goose/Guangdong/1/1996 (Gs/Gd) through genetic reassortments with several low pathogenicity avian influenza viruses present in populations of Anseriformes and Charadriiformes orders. This review addresses these issues by thoroughly analysing available epidemiological databases and specialized literature reviews. This project explores the mechanisms behind the resurgence of the H5N1 virus. It provides a comprehensive overview of the origin, timeline and factors contributing to its prevalence among wild bird populations on the American continent.

Indexed as

Influenza A Virus, H5N1 SubtypeInfluenza in BirdsAmericasAnimal MigrationAnimalsAnseriformesBirdsDisease OutbreaksReassortant VirusesVirulenceA/Goose/Guangdong/1/1996 (Gs/Gd) lineageevolution influenza virusmigratory patternsmolecular markersoutbreakswild birds

Identifiers

PMID40279164
PMCPMC12032427

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.