Evidence map›Paper›PMID 40279059›Full record

ArticleCJEM2025

A multicenter prospective cohort study evaluating 30-day outcomes after an emergency department visit for hyperglycemia in Canadian adults with type 1 or 2 diabetes.

Justin W Yan, Kristine Van Aarsen, Joe Thorne, Igor Karp, Tamara Spaic, Selina L Liu, Nicolas Woods, Ian G Stiell, Network of Canadian Emergency Researchers (NCER)

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in CJEM, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Justin W YanDivision of Emergency Medicine, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. Justin.Yan@lhsc.on.ca.ORCID 0000-0003-4668-5124
Kristine Van AarsenDivision of Emergency Medicine, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Joe ThorneDivision of Emergency Medicine, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Igor KarpDepartment of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Tamara SpaicLawson Health Research Institute, London, ON, Canada.
Selina L LiuLawson Health Research Institute, London, ON, Canada.
Nicolas WoodsDivision of Emergency Medicine, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Ian G StiellDepartment of Emergency Medicine, University of Ottawa, Ottawa, ON, Canada.
Network of Canadian Emergency Researchers (NCER)

Funding

Academic Medical Organization of Southwestern Ontario #INN21-004
6 · The paper itself

Abstract

objectivesPrevious retrospective studies have demonstrated that patients with sub-optimally controlled diabetes have higher healthcare resource utilization in emergency department (ED) management of hyperglycemia compared to those with good glycemic control. This study's objective was to prospectively describe 30-day outcomes including return visits and hospitalizations after an initial ED visit for hyperglycemia.

methodsWe conducted a multicenter prospective cohort study of adults ≥ 18 years at four Ontario academic EDs diagnosed with hyperglycemia, diabetic ketoacidosis, or hyperosmolar hyperglycemic state. The primary outcome was an unplanned repeat ED visit for hyperglycemia within 30 days of index visit. We conducted telephone follow-up at 14 and 30 days to determine additional outcomes. Data were summarized using descriptive statistics.

resultsThere were 657 ED visits for hyperglycemia representing 594 unique patients. Mean (SD) age was 52.0 (18.2) years, 53.2% were male. Within 30 days, 96 (14.7%) had a return ED visit for hyperglycemia, 49 (7.5%) were hospitalized, and 4 (0.6%) died. We were able to contact 383 (58.3%) patients by telephone at 14 days and 275 (41.9%) at 30 days. Of these, 68.3% self-identified as Caucasian/White, while 6.3% were Indigenous. 44.9% reported an annual household income below $50,000. 29.1% of working patients took time off following their index visit.

conclusionThis prospective study describes 30-day outcomes and healthcare utilization of ED patients presenting for hyperglycemia. ED clinicians should be aware of the potential for subsequent healthcare utilization and risk for readmission and intervene as appropriate to reduce adverse outcomes in patients with diabetes presenting with hyperglycemia.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2Emergency Service, HospitalHyperglycemiaAdultAgedCanadaEmergency Room VisitsFemaleFollow-Up StudiesHumansMaleMiddle AgedOntarioProspective StudiesTime FactorsDiabetesEmergency departmentHyperglycemiaPatient outcomes

Identifiers

PMID40279059
PMCPMC12279581

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.