Evidence map›Paper›PMID 40279024›Full record

ArticleHealth economics review2025

Epidemiology and hospitalization costs of chronic kidney disease in Romania.

Ildiko Aliz Bradacs, László-István Bába, László Lorenzovici, Andreea Mihaela Precup, Szabolcs Farkas- Ráduly, Gyongyi Tar, Vasile Nastase, Lucia Georgeta Daina, Raul Bozu, Gyula Jozsef Nagy and 6 more

Abstract read
In one paragraph

Article in Health economics review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ildiko Aliz BradacsDoctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, Oradea, 410087, Romania.ORCID http://orcid.org/0009-0000-6467-0685
László-István BábaSyreon Research Romania, Tirgu Mures, Romania.ORCID http://orcid.org/0000-0001-8682-0429
László LorenzoviciSyreon Research Romania, Tirgu Mures, Romania. lorenzovici@syreon.ro.ORCID http://orcid.org/0000-0002-1817-2674
Andreea Mihaela PrecupSyreon Research Romania, Tirgu Mures, Romania.
Szabolcs Farkas- RádulySyreon Research Romania, Tirgu Mures, Romania.ORCID http://orcid.org/0009-0002-5669-0218
Gyongyi TarSapientia Hungarian University of Transilvania, Targu Mures, Romania.
Vasile NastaseFundeni Clinical Institute, Bucharest, Romania.
Lucia Georgeta DainaDepartment of Psycho-Neurosciences and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.ORCID http://orcid.org/0000-0002-6049-4095
Raul BozuClinical County Emergency Hospital of Oradea, Oradea, Romania.
Gyula Jozsef NagyDoctoral School, Faculty of Health Sciences, University of Pecs, Pecs, Hungary.ORCID http://orcid.org/0009-0005-3869-6263
Dimitrie Cristian SiriopolȘtefan cel Mare, University of Suceava, Suceava, Romania.ORCID http://orcid.org/0000-0003-1297-0648
Dorel SandescAnaesthesia and Intensive Care Medicine Department, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.ORCID http://orcid.org/0000-0003-0349-8257
Ovidiu Horea BedreagAnaesthesia and Intensive Care Medicine Department, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.ORCID http://orcid.org/0000-0002-3432-9168
Florin BuicuGeorge Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142, Targu Mures, Romania.ORCID http://orcid.org/0000-0002-7378-5756
Gabriel MircescuDepartment of Nephrology, "Carol Davila" University of Medicine and Pharmacy, 050474, Bucharest, Romania.ORCID http://orcid.org/0000-0002-8606-3699
Gener IsmailDepartment of Nephrology, "Carol Davila" University of Medicine and Pharmacy, 050474, Bucharest, Romania.ORCID http://orcid.org/0000-0003-3306-189X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease or chronic renal failure is a progressive condition defined as abnormalities of kidney structure or function, present for longer than 3 months. It is estimated to affect more than 10% of the general population worldwide. Management of CKD represents an especially large burden for the health systems of low- and middle-income countries, and it has been recognized as a leading public health problem. Previous research articles reported an age-adjusted prevalence of 7.6% for Romania, but the hospital costs generated by CKD are unknown. The present research article aimed to measure the hospital costs and one-year national healthcare budget impact of CKD, excepting the chronic care costs of RRTs.

methodsIn this retrospective study we reviewed the electronic health records of 4 University, 3 County and 5 City hospitals from 1

resultsIn 2019 a total number of 229 276 cases reported chronic kidney disease in Romania. The average hospital costs per patient episode was €917.1, with significantly higher costs in cases with complications or higher severity grades. The total hospitalization cost-related budget impact in 2019 was €210 million.

conclusionsThe high hospitalization costs of CKD (representing 2.6% of the NHIH budget, not considering the funds for sick leave) cause major impact on the national health payer`s budget. Preventive strategies, early diagnosis and management as well as health education measures could act as means of mitigation. Our results should warn the public health policy decision makers about the importance of this disease.

Indexed as

Budget impactChronic kidney diseaseDialysisHospitalization cost

Identifiers

PMID40279024
PMCPMC12032732

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.