Evidence map›Paper›PMID 40278956›Full record

ArticleVeterinary research communications2025

Description of a sheep abortion caused by atypical genotype of Toxoplasma gondii in the state of Mato Grosso, Brazil.

Ícaro Guilherme Dos Santos, Marlon Ribeiro, João Paulo da Silva Cavasani, Luana Dias O Nascimento, Bernardo Nassau de Souza, Rafaela Mallmann-Bohn, Fábio Bernardo Schein, João Fabio Soares, Beatriz Souza Lima Nino, João Luis Garcia and 4 more

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Article in Veterinary research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

14 authors.

Ícaro Guilherme Dos SantosLaboratory of Veterinary Pathology, Federal University of Mato Grosso (UFMT), Cuiabá, Mato Grosso, Brazil.
Marlon RibeiroLaboratory of Veterinary Pathology, Federal University of Mato Grosso (UFMT), Cuiabá, Mato Grosso, Brazil.
João Paulo da Silva CavasaniLaboratory of Veterinary Pathology, Federal University of Mato Grosso (UFMT), Cuiabá, Mato Grosso, Brazil.
Luana Dias O NascimentoLaboratory of Veterinary Pathology, Federal University of Mato Grosso (UFMT), Cuiabá, Mato Grosso, Brazil.
Bernardo Nassau de SouzaLaboratory of Protozoology and Vector-Borne Rickettsiosis, Faculty of Veterinary Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Rafaela Mallmann-BohnLaboratory of Protozoology and Vector-Borne Rickettsiosis, Faculty of Veterinary Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Fábio Bernardo ScheinLaboratory of Microbiology and Infectious Diseases, Faculty of Veterinary Medicine of Cuiabá University (UNIC), Cuiabá, Mato Grosso, Brazil.
João Fabio SoaresLaboratory of Protozoology and Vector-Borne Rickettsiosis, Faculty of Veterinary Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Beatriz Souza Lima NinoDepartment of Preventive Veterinary Medicine. Laboratory of Protozoology and Infectious Disease, Londrina State University (UEL), Londrina, Paraná, Brazil.
João Luis GarciaDepartment of Preventive Veterinary Medicine. Laboratory of Protozoology and Infectious Disease, Londrina State University (UEL), Londrina, Paraná, Brazil.
Daniel Felipe Barrantes MurilloDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, 36849, USA.
Tatiane Terumi Negrão WatanabeAntech Diagnostics, 12401 West Olympic Blvd, Los Angeles, CA, 90064, USA.
Daniel Moura de AguiarLaboratory of Virology and Rickettsiosis, Federal University of Mato Grosso (UFMT), Cuiabá, Mato Grosso, Brazil.
Caroline Argenta PescadorLaboratory of Veterinary Pathology, Federal University of Mato Grosso (UFMT), Cuiabá, Mato Grosso, Brazil. carolpescador@yahoo.com.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasma gondii is one of the major causes of abortion in sheep in many countries. We report an episode of a novel atypical genotype of T. gondii-associated abortion in a sheep flock belonging to the Veterinary School Hospital of the University of Cuiabá located in Midwestern Brazil. The group of animals was comprised of 15 adult sheep, and one abortion was detected in a gestating ewe. T. gondii indirect immunofluorescence assay performed in serum samples yielded an antibody titer of 1:8192 in the affected dam indicating an acute phase of infection. The aborted fetus and placenta were submitted for necropsy. The only significant gross findings were the placental cotyledons with white foci. Microscopic findings included multifocal necrotizing encephalitis with intralesional protozoal cysts in the fetus's brain and moderate multifocal lymphoplasmacytic necrotizing placentitis. Tissue samples of the fetus and placenta had a positive PCR result for T. gondii. Restriction fragment length polymorphism (RFLP) genotyping using markers (SAG1, 5'-SAG2, 3'-SAG2, Alt.SAG2, SAG3, BTUB, GRA6, c22-8, c29-2, L358, PK1, and APICO) was carried out and the results were consistent with an atypical genotype.

Indexed as

Abortion, VeterinarySheep DiseasesToxoplasmaToxoplasmosis, AnimalAborted FetusAnimalsBrazilFemaleGenotypePlacentaPolymorphism, Restriction Fragment LengthPregnancySheepEncephalitisFetal lossMolecular diagnosisPlacentitisProtozoan

Identifiers

PMID40278956

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.