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ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2025

Comparing residual thrombosis and venous thromboembolism outcomes between patients treated with or without anticoagulant therapy for acute distal lower-limb deep vein thrombosis after total hip arthroplasty.

Shine Tone, Yohei Naito, Hiroki Wakabayashi, Akihiro Sudo, Masahiro Hasegawa

Abstract readComparative Study
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In one paragraph

Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Shine ToneDepartment of Orthopaedic Surgery, Graduate School of Medicine, Mie University, Tsu, Japan. s-tone@med.mie-u.ac.jp.
Yohei NaitoDepartment of Orthopaedic Surgery, Graduate School of Medicine, Mie University, Tsu, Japan.
Hiroki WakabayashiDepartment of Orthopaedic Surgery, Graduate School of Medicine, Mie University, Tsu, Japan.
Akihiro SudoYonaha Okanoue Hospital, Kuwana, Japan.
Masahiro HasegawaDepartment of Orthopaedic Surgery, Graduate School of Medicine, Mie University, Tsu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate the necessity of anticoagulant therapy with an Xa inhibitor for asymptomatic acute distal lower-limb deep vein thrombosis (DVT) detected on ultrasonography after total hip arthroplasty (THA).

methodsAfter exclusions, patients who underwent primary cementless THA were divided into treatment and no-treatment groups based on whether they received anticoagulant therapy with an Xa inhibitor for asymptomatic acute distal lower-limb DVT. Residual distal lower-limb DVT at 3 months, incidence of proximal DVT, and symptomatic venous thromboembolism (VTE) after THA were compared between the groups.

resultsA total of 574 patients met the inclusion criteria (treatment group, n = 287; no-treatment group, n = 287). Residual distal lower-limb DVT at 3 months was detected in 3 patients (1.0%) in the treatment group and in 10 patients (3.5%) in the no-treatment group. No symptomatic VTE was observed in either group. No significant difference was observed between the two groups, although the no-treatment group tended to have a higher residual rate of acute distal lower-limb DVT.

conclusionThe necessity of anticoagulant therapy for asymptomatic acute distal lower-limb DVT was not confirmed.

Indexed as

AnticoagulantsArthroplasty, Replacement, HipFactor Xa InhibitorsPostoperative ComplicationsVenous ThromboembolismVenous ThrombosisAgedFemaleHumansLower ExtremityMaleMiddle AgedRetrospective StudiesTreatment OutcomeUltrasonographyAnticoagulantsFactor Xa InhibitorsAnticoagulantsArthroplastyDeep vein thrombosisUltrasonographyVenous thromboembolism

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.