Evidence map›Paper›PMID 40278912›Full record

ArticleRheumatology international2025

Anterior segment alterations in fibromyalgia syndrome: a cross-sectional study on dry eye disease, meibomian gland dysfunction, and astigmatism.

Duygu Topaktaş Emekli, Eda Sahutoglu, Gülşah Yaşa Öztürk, Burhan Fatih Kocyigit

Abstract read
In one paragraph

Article in Rheumatology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Duygu Topaktaş EmekliDepartment of Ophthalmology, Adana City Training and Research Hospital, Adana, Türkiye.ORCID http://orcid.org/0000-0003-0610-2422
Eda SahutogluDepartment of Ophthalmology, Adana City Training and Research Hospital, Adana, Türkiye.ORCID http://orcid.org/0009-0006-3146-6577
Gülşah Yaşa ÖztürkFaculty of Medicine, Department of Physical Medicine and Rehabilitation, University of Health Sciences, Adana City Training and Research Hospital, Adana, Türkiye.ORCID http://orcid.org/0000-0002-9033-5095
Burhan Fatih KocyigitFaculty of Medicine, Department of Physical Medicine and Rehabilitation, University of Health Sciences, Adana City Training and Research Hospital, Adana, Türkiye. bfk2701@hotmail.com.ORCID http://orcid.org/0000-0002-6065-8002

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibromyalgia syndrome (FMS) is an ongoing disorder distinguished by its multifaceted characteristics. There has been increasing interest in its ophthalmologic aspects. This study evaluated the anterior segment parameters of the eye in patients with FMS, comparing them to healthy controls. Furthermore, correlations with disease activity were analyzed. This research was structured as a cross-sectional and comparative analysis. Data was collected at a tertiary care education and research hospital from August 20, 2024, to November 15, 2024. The participants' central corneal thickness, uncorrected and best-corrected visual acuities, refraction parameters, intraocular pressure, meibomian gland dysfunction (MGD), and dry eye disease (DED) parameters were evaluated. There were no significant differences in visual acuity, spherical equivalent, intraocular pressure, and central corneal thickness between FMS and healthy controls (p > 0.05). The median astigmatism in the right eye (diopter) was - 0.50 (-8.25-0) for the FMS group and - 0.12 (-1.75-0.50) for the control group (p = 0.012). The left eye data were - 0.50 (-2-1.50) for the FMS group and 0 (-1.75-0.75) for the control group (p = 0.056). MGD was identified in 26 (36.6%) individuals in the FMS group, whereas it was identified in 3 (4.3%) participants in the control group (p < 0.001). DED was detected in 43 (60.6%) participants in the FMS group and 15 (21.4%) participants in the control group (p < 0.001). FMS patients had higher rates of astigmatism, MGD, and DED compared to healthy controls, underscoring the necessity for routine anterior segment assessments. These data suggest possible ocular involvement in FMS, which warrants further research.

Indexed as

Anterior Eye SegmentAstigmatismDry Eye SyndromesFibromyalgiaMeibomian Gland DysfunctionAdultCase-Control StudiesCorneaCross-Sectional StudiesFemaleHumansIntraocular PressureMaleMiddle AgedVisual AcuityAstigmatismDry eye diseaseEye diseasesFibromyalgiaMeibomian gland dysfunctionOphthalmology

Identifiers

PMID40278912
PMCPMC12031864

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.