ArticleAesthetic plastic surgery2025
Postoperative Intermittent Fasting Improves Outcome of Autologous Fat Grafting in Mice.
Article in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Pancreatic-liver crosstalk, novel molecular mediators, and 2025 therapeutic breakthroughs.World journal of methodology · 2026Review
- Intermittent fasting triggers interorgan communication to improve the progression of diabetic osteoporosis.Gut microbes · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundAutologous fat grafting confronts challenges of inconsistent retention and complications. Intermittent fasting (IF), an emerging dietary management strategy, shows potential in tissue repair and fat metabolism, and yet to know in fat grafting.
objectivesThe aim of this study is to address the impact of 16:8 IF on the outcome of fat grafting in mice.
methodsMale C57BL/6 mice were randomly assigned to postoperative IF regimen group (n = 24) and ad libitum group with unrestricted feeding (n = 24). For postoperative IF group, animals were put on a feeding schedule with 8 hours of unrestricted access to standard diet per day followed by 16-h fasting period after fat grafting. Fat grafts were harvested at 2, 4 and 12 weeks postoperatively. We addressed the mass retention and graft quality through weighting and ultrasound examination. Histological remodeling of fat grafts was evaluated by Masson staining and immunofluorescence staining.
resultsIn comparison with unrestricted feeding, postoperative IF strategies improved the mass retention of fat grafts, and optimized the outcomes characterized by enhanced adipogenesis, accelerated revascularization, facilitated M2 macrophage infiltration as well as reduced fibrosis and oil cyst formation.
conclusionPostoperative IF improved the retention and outcomes of fat grafting in mice, and could be suggested as a dietary intervention strategy after fat grafting clinically. NO LEVEL ASSIGNED: This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
Indexed as
Identifiers
40278876What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.