ArticleTropical medicine and infectious disease2025
Community-Based Tuberculosis Preventive Treatment Among Child and Adolescent Household Contacts in Ethiopia.
Article in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07313995 (Digital Health Intervention in Improving Preventive Treatment Initiation and Completion Among Close Contacts of Tuberculosis Patients in South Ethiopia), which is not on this map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Digital Health Intervention in Improving Preventive Treatment Initiation and Completion Among Close Contacts of Tuberculosis Patients in South Ethiopia
Who cites it
3 citing papers in PubMed.
- Perceived benefits of community-based TB preventive treatment in children in Uganda: "When she sees other children getting the same medication, she will feel not alone."PLOS global public health · 2026Article
- Tuberculosis Preventive Treatment Coverage in India: An Ignored Yellow Alert?Indian journal of pediatrics · 2025Article
- Non-adherence and its predictors among pediatric household contacts on tuberculosis preventive therapy in the 3HP era: A multicenter observational study.Therapeutic advances in infectious diseaseArticle
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are limited studies on the community-based outcomes of tuberculosis (TB) preventive treatment (TPT) among children and adolescent contacts <15 years in Ethiopia. Our objective was to assess TPT uptake and completion rates among eligible under-15-year-old TB household contacts through an enhanced community-based model of interventions. The study was conducted between July 2021 and June 2022 in twenty primary health care units in the Sidama and Southern Nations, Nationalities, and Peoples' Region (SNNPR) regions. A total of 4367 (99.2%) household contacts of 1069 bacteriologically confirmed PTB index cases were symptomatically screened for TB by trained health extension workers (HEWs) at the community level. A total of 696 (15.9%) symptomatic contacts were identified, of which 694 (99.7%) were evaluated for TB, resulting in 60 (8.6%) TB cases. A total of 1567 (95.3%) asymptomatic children and adolescent contacts <15 years of age were initiated on TPT (88.8%) at health posts in the community. After the interventions, there was a significant increase in contact screening coverage (95.6% vs. 99.2%, Odds Ratio (OR), 5.54; 95% Confidence interval (CI), 2.93-10.13) and TPT uptake (81.7% vs. 95.4%; OR, 4.67; 95% CI, 2.54-8.23). The TPT completion rate was also 98.1% (of 1567). The TPT completion rate at health posts in the community was higher than the rate at health centers (99.4% vs. 88.0%; OR, 20.95; 95% CI, 8.97-52.71). TPT uptake and completion in children and adolescent contacts could be improved remarkably with the implementation of an enhanced community-based model of intervention in high-TB-burden districts.
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