Evidence map›Paper›PMID 40278737›Full record

ArticleSports (Basel, Switzerland)2025

Effect of Metabolic Stress to High-Load Exercise on Muscle Damage, Inflammatory and Hormonal Responses.

Séverine Stragier, Jacques Duchateau, Frédéric Cotton, Julie Smet, Fleur Wolff, Jérémy Tresnie, Alain Carpentier

Abstract read
In one paragraph

Article in Sports (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Insulin Resistance and Inflammation.International journal of molecular sciences · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Séverine StragierResearch Unit in Cardio-Respiratory Physiology, Exercise & Nutrition, Faculty of Human Movement Sciences, Université libre de Bruxelles, 1070 Brussels, Belgium.ORCID 0009-0000-3552-1752
Jacques DuchateauLaboratory of Applied Biology and Neurophysiology, Faculty of Human Movement Sciences, Université libre de Bruxelles, 1070 Brussels, Belgium.
Frédéric CottonLaboratoire Hospitalier Universitaire de Bruxelles, Clinical Chemistry, Université libre de Bruxelles, 1070 Brussels, Belgium.
Julie SmetLaboratoire Hospitalier Universitaire de Bruxelles, Immunology, Université libre de Bruxelles, 1070 Brussels, Belgium.
Fleur WolffLaboratoire Hospitalier Universitaire de Bruxelles, Clinical Chemistry, Université libre de Bruxelles, 1070 Brussels, Belgium.
Jérémy TresnieLaboratoire Hospitalier Universitaire de Bruxelles, Immunology, Université libre de Bruxelles, 1070 Brussels, Belgium.
Alain CarpentierResearch Unit in Cardio-Respiratory Physiology, Exercise & Nutrition, Faculty of Human Movement Sciences, Université libre de Bruxelles, 1070 Brussels, Belgium.ORCID 0000-0003-4032-2699

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess the impact of metabolic stress on blood lactate, muscle damage, inflammatory and hormonal responses following a high-load (70% maximum) strength training session, we compared two methods with a similar number of repetitions but that differed by their metabolic demand: the 3/7 method consisting in two series of five sets of an increasing number of repetitions (3 to 7) with a short inter-set interval (15 s) and the 8 × 6 method that comprises eight sets of six repetitions with a longer inter-set interval (2.5 min). Blood concentrations in lactate, creatine kinase (CK), myoglobin (MB), interleukine-6 (IL-6), leukocytes, growth hormone (GH), insulin-like growth factor-1 (IGF-1) and cortisol were determined before and after each session. Lactate concentration increased more (11.9 vs. 3.1 mmol/L;

Indexed as

blood biomarkerslactatemuscle regenerationstrength training methods

Identifiers

PMID40278737
PMCPMC12031578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.