Evidence map›Paper›PMID 40278703›Full record

Observational studyToxins2025

Autonomic Dysfunction and Blood Pressure Variability in Botulinum Intoxication: A Prospective Observational Study from a Single-Center Italian Outbreak.

Giuseppe Miceli, Giuliano Cassataro, Vito Volpe, Emanuela Fertitta, Carmelinda Canale, Lucia Tomaiuolo, Melania Blasco, Mariagrazia Stella, Matteo Velardo, Maurizio Renda

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giuseppe MiceliDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), Università degli Studi di Palermo, Piazza delle Cliniche 2, 90127 Palermo, Italy.ORCID 0000-0002-4797-2523
Giuliano CassataroU.O.C. of Medicine and Pneumology, Fondazione Istituto G. Giglio, Contrada Pollastra, 90015 Cefalù, Italy.
Vito VolpeU.O.C. of Medicine and Pneumology, Fondazione Istituto G. Giglio, Contrada Pollastra, 90015 Cefalù, Italy.
Emanuela FertittaU.O.C. of Medicine and Pneumology, Fondazione Istituto G. Giglio, Contrada Pollastra, 90015 Cefalù, Italy.
Carmelinda CanaleU.O.C. of Medicine and Pneumology, Fondazione Istituto G. Giglio, Contrada Pollastra, 90015 Cefalù, Italy.
Lucia TomaiuoloU.O.C. of Medicine and Pneumology, Fondazione Istituto G. Giglio, Contrada Pollastra, 90015 Cefalù, Italy.
Melania BlascoU.O.C. of Medicine and Pneumology, Fondazione Istituto G. Giglio, Contrada Pollastra, 90015 Cefalù, Italy.
Mariagrazia StellaU.O.C. of Medicine and Pneumology, Fondazione Istituto G. Giglio, Contrada Pollastra, 90015 Cefalù, Italy.
Matteo VelardoEuropean School of Obstetric Anesthesia, EESOA Simulation Center, 00042 Rome, Italy.
Maurizio RendaU.O.C. of Medicine and Pneumology, Fondazione Istituto G. Giglio, Contrada Pollastra, 90015 Cefalù, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Botulinum neurotoxin (BoNT) intoxication is a rare but severe condition that is characterized by autonomic and neuromuscular dysfunction. This study aimed to evaluate autonomic impairment and blood pressure variability in patients with botulinum intoxication during an outbreak, compared to healthy controls, and to assess their progression over a six-month follow-up period.

Indexed as

Autonomic Nervous SystemAutonomic Nervous System DiseasesBlood PressureBotulinum ToxinsBotulismHypotension, OrthostaticAdultAgedDisease OutbreaksHumansItalyMaleMiddle AgedProspective StudiesBotulinum Toxinsbotulindysautonomic dysfunctionerectile dysfunctionorthostatic hypotensiontoxin

Identifiers

PMID40278703
PMCPMC12031082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.