Evidence map›Paper›PMID 40278698›Full record

ArticleToxins2025

The Effects of Botulinum Toxin A Injections on Patients with Radiogenic Lower Urinary Tract Symptoms.

Anke K Jaekel, Ann-Christin Brüggemann, John Bitter, Franziska Knappe, Ruth Kirschner-Hermanns, Stephanie C Knüpfer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anke K JaekelDepartment of Neuro-Urology, Clinic for Urology, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0001-7359-4047
Ann-Christin BrüggemannClinic for Urology and Pediatric Urology, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
John BitterDepartment of Neuro-Urology, Johanniter Neurological Rehabilitation Center Godeshoehe GmbH, 53177 Bonn, Germany.
Franziska KnappeDepartment of Neuro-Urology, Johanniter Neurological Rehabilitation Center Godeshoehe GmbH, 53177 Bonn, Germany.
Ruth Kirschner-HermannsDepartment of Neuro-Urology, Clinic for Urology, University Hospital Bonn, 53127 Bonn, Germany.
Stephanie C KnüpferDepartment of Neuro-Urology, Clinic for Urology, University Hospital Bonn, 53127 Bonn, Germany.

Funding

Open Access Publication Fund of the University of Bonn no Grant Number
6 · The paper itself

Abstract

Botulinum toxin A (BTX-A) injection into the detrusor vesicae is an established therapy for neurogenic lower urinary tract dysfunction as well as idiopathic overactive bladder. Pelvic radiotherapy causes comparable lower urinary tract symptoms (LUTS) in a third of radiated patients. Little is known about the effects of BTX-A injections into the detrusor vesicae in the management of radiogenic LUTS. Our aim was to assess the effect of BTX A injections on these symptoms and related quality of life.

Indexed as

Botulinum Toxins, Type ALower Urinary Tract SymptomsNeuromuscular AgentsRadiation InjuriesAdultAgedFemaleHumansMaleMiddle AgedQuality of LifeRetrospective StudiesTreatment OutcomeUrinary BladderUrodynamicsBotulinum Toxins, Type ANeuromuscular AgentsbladderBotulinum toxin ALUTSquality of liferadiogenic cystitis

Identifiers

PMID40278698
PMCPMC12031092

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.