Evidence map›Paper›PMID 40278695›Full record

ArticleToxins2025

A 20-Year Retrospective Analysis of Plant Poisoning Cases at the Naval Hospital, Varna, Bulgaria.

Stanila Stoeva-Grigorova, Maya Radeva-Ilieva, Stela Dragomanova, Gabriela Kehayova, Simeonka Dimitrova, Simeon Marinov, Petko Marinov, Marieta Yovcheva, Diana Ivanova, Snezha Zlateva

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Stanila Stoeva-GrigorovaDepartment of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, Varna 9002, Bulgaria.ORCID 0000-0002-0528-0289
Maya Radeva-IlievaDepartment of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, Varna 9002, Bulgaria.ORCID 0000-0001-5778-4043
Stela DragomanovaDepartment of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, Varna 9002, Bulgaria.ORCID 0000-0003-1845-2753
Gabriela KehayovaDepartment of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, Varna 9002, Bulgaria.ORCID 0000-0002-5041-1620
Simeonka DimitrovaDepartment of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, Varna 9002, Bulgaria.
Simeon MarinovDepartment of Urology, Faculty of Medicine, Medical University of Varna, Varna 9002, Bulgaria.
Petko MarinovDepartment of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, Varna 9002, Bulgaria.
Marieta YovchevaClinical Toxicology Department, Naval Hospital, Varna 9000, Bulgaria.ORCID 0000-0002-0744-3766
Diana IvanovaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, Varna 9002, Bulgaria.ORCID 0000-0002-4502-081X
Snezha ZlatevaDepartment of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, Varna 9002, Bulgaria.

Funding

NextGenerationEU BG-RRP-2.004-0009-C02
6 · The paper itself

Abstract

The nature and epidemiology of plant intoxications are still not well understood, with recent data being limited. The present study aims to report cases of plant poisoning in the clinical practice of the Clinical Toxicology Department at the Naval Hospital-Varna, Bulgaria, over a 20-year period (2003-2023). A documentary retrospective analysis of the hospitalized cases of poisoning with poisonous plants and their grouping into toxidromes was performed. During the study period, patients with plant poisoning admitted to our hospital unit accounted for 0.35% of a total of 12,857 hospitalized individuals. The distribution across the toxidromes based on clinical presentation revealed the highest frequency of anticholinergic, cyanogen, and ricin toxidromes. The majority of the intoxications resulted from unintentional exposure to plant toxins in adult individuals. Most cases followed a mild to severe clinical course, with patient discharge occurring between 2 and 5 days. No fatalities were recorded, thanks to the reported treatment methods. A relatively low incidence of plant-related poisonings was observed, with their predominant manifestations affecting the gastrointestinal, nervous, and cardiovascular systems. Increased reporting of epidemiological data and clinical experiences in the management of plant intoxications would substantially enhance researchers' understanding of them and facilitate the development of a standardized treatment protocol.

Indexed as

Plant PoisoningAdolescentAdultAgedBulgariaChildChild, PreschoolFemaleHospitalizationHumansIncidenceMaleMiddle AgedRetrospective StudiesYoung Adultanticholinergic toxidromecyanogen toxidromeintoxicationsplantsricin toxidrometoxidromes

Identifiers

PMID40278695
PMCPMC12031007

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.