Evidence map›Paper›PMID 40278650›Full record

ArticleToxins2025

Enhancing the Efficacy of Melanoma Treatment: The In Vitro Chemosensitising Impact of

Giovanni Paolino, Matteo Riccardo Di Nicola, Carla Raggi, Serena Camerini, Marialuisa Casella, Luca Pasquini, Cristiana Zanetti, Vincenzo Russo, Santo Raffaele Mercuri, Luana Lugini and 1 more

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Giovanni PaolinoUnit of Dermatology and Cosmetology, IRCCS San Raffaele Hospital, Via Olgettina 60, 20132 Milan, Italy.
Matteo Riccardo Di NicolaIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154 Turin, Italy.ORCID 0000-0001-7199-0804
Carla RaggiDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.
Serena CameriniCore Facilities, Istituto Superiore di Sanità, 00161 Rome, Italy.
Marialuisa CasellaCore Facilities, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0003-0245-6709
Luca PasquiniCore Facilities, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-3484-6288
Cristiana ZanettiDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0001-5530-0893
Vincenzo RussoUnit of Immuno-Biotherapy of Melanoma and Solid Tumors, IRCCS San Raffaele Hospital, Via Olgettina 60, 20132 Milan, Italy.
Santo Raffaele MercuriUnit of Dermatology and Cosmetology, IRCCS San Raffaele Hospital, Via Olgettina 60, 20132 Milan, Italy.
Luana LuginiDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-8778-2601
Cristina FedericiDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0001-6366-0231

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research on viper venom has expanded into diverse medical applications, including cancer treatment. This study investigates the potential of

Indexed as

Antineoplastic AgentsMelanomaViper VenomsAnimalsCell Line, TumorCell SurvivalCisplatinDrug Resistance, NeoplasmDrug SynergismHumansViperaViperidaeAntineoplastic AgentsCisplatinViper Venomsantitumor peptideschemoresistancecisplatincytotoxicitymetalloproteinasesmetastasisnose-horned vipersnake venomtherapeutic adjuvantsviper

Identifiers

PMID40278650
PMCPMC12031473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.