ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
Intraoperative Fast Adaptive Focus Tracking Robotic OCT Enables Real-Time Tumor Grading and Large-Area Microvascular Imaging in Human Spinal Cord Surgery.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Intensity Variance-Guided Automated Robotic Optical Coherence Tomography System for Ophthalmic Applications.Journal of biophotonics · 2026Article
- Depth-of-focus enhancement in optical coherence tomography via a cascaded image registration and fusion network for multi-focus imaging.Journal of biomedical optics · 2026Article
- Intraoperative Fast Adaptive Focus Tracking Robotic OCT Enables Real-Time Tumor Grading and Large-Area Microvascular Imaging in Human Spinal Cord Surgery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
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17 authors.
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Abstract
Current surgical procedures for spinal cord tumors lack in vivo high-resolution multifunctional imaging systems, hindering precise tumor resection. This study introduces the fast adaptive focus tracking robotic optical coherence tomography (FACT-ROCT) system, which provides real-time, artifact-free imaging during surgery, addressing motion artifacts and resolution degradation. Imaging occurs in 22 patients, including 13 with gliomas (WHO grade I-IV). This represents the first in situ OCT imaging of human spinal cord tumors, enabling the differentiation of tumor types in real-time. The standard deviation of the attenuation coefficient serves as a physical marker, achieving 90.2% ± 2.7% accuracy in distinguishing high- from low-grade gliomas intraoperatively at a threshold of 0.75 ± 0.01 mm
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