Evidence map›Paper›PMID 40278627›Full record

ReviewToxics2025

Effects of Environmental Pollutants on Tryptophan Metabolism.

Hongyang Hu, Xiaoxun Lu, Miaoliang Wu, Zhi Bai, Xiaoshan Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hongyang HuSchool of Public Health, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, China.ORCID 0009-0006-9991-5834
Xiaoxun LuSchool of Public Health, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, China.
Miaoliang WuSchool of Public Health, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, China.
Zhi BaiSchool of Public Health, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, China.
Xiaoshan LiuSchool of Public Health, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, China.ORCID 0000-0002-5291-642X

Funding

Dongguan Science and Technology of Social Development Program 20231800935952National Natural Science Foundation of China 82373614Natural Science Foundation of Guangdong Province 2022A1515010214
6 · The paper itself

Abstract

Tryptophan (Trp) is an important essential amino acid that plays a variety of physiological functions in the human body, including being a precursor of neurotransmitter and participating in immune regulation. Currently, more and more studies show that some pollutants in the environment can affect the metabolism of Trp and consequently affect human health. The present paper offers a comprehensive overview of prior research investigating the impact of environmental pollutants, including inorganic and organic contaminants, microplastics, and nanoplastics on the nervous system, immune system, digestive system, and maternal-fetal pregnancy, revealing their detrimental effects on Trp metabolism and human well-being.

Indexed as

5-HT pathwaykynurenine pathwaytryptophan

Identifiers

PMID40278627
PMCPMC12031123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.