Evidence map›Paper›PMID 40278591›Full record

ReviewToxics2025

Emission Characteristics of Volatile Organic Compounds from Material Extrusion Printers Using Acrylonitrile-Butadiene-Styrene and Polylactic Acid Filaments in Printing Environments and Their Toxicological Concerns.

Yuan Gao, Yawei Xue, Chenyang Sun, Luhang She, Ying Peng

Abstract readReview
In one paragraph

Review in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuan GaoInstrumentation and Service Center for Science and Technology, Beijing Normal University, Zhuhai 519087, China.
Yawei XueInstrumentation and Service Center for Science and Technology, Beijing Normal University, Zhuhai 519087, China.
Chenyang SunResearch and Development Center for Watershed Environmental Eco-Engineering, Advanced Institute of Natural Sciences, Beijing Normal University, Zhuhai 519087, China.
Luhang SheResearch and Development Center for Watershed Environmental Eco-Engineering, Advanced Institute of Natural Sciences, Beijing Normal University, Zhuhai 519087, China.
Ying PengResearch and Development Center for Watershed Environmental Eco-Engineering, Advanced Institute of Natural Sciences, Beijing Normal University, Zhuhai 519087, China.

Funding

Research Start-up fund of Beijing Normal University at Zhuhai 28714-111032101; 28707-310432103
6 · The paper itself

Abstract

The utilization of 3D printing releases a multitude of harmful gas pollutants, posing potential health risks to operators. Materials extrusion (ME; also known as fused deposition modeling (FDM)), a widely adopted 3D printing technology, predominantly employs acrylonitrile-butadiene-styrene (ABS) and polylactic acid (PLA) as printing materials, with the respective market shares of these materials reaching approximately 75%. The extensive usage of ABS and PLA during the ME process leads to significant volatile organic compound (VOC) emissions, thereby deteriorating the quality of indoor air. Nevertheless, information regarding the emission characteristics of VOCs and their influencing factors, as well as the toxicological impacts of the printing processes, remains largely unknown. Herein, we thoroughly reviewed the emission characteristics of VOCs released during ME printing processes using ABS and PLA in various printing environments, such as chambers, laboratories, and workplaces, as well as their potential influencing factors under different environmental conditions. A total of 62 VOC substances were identified in chamber studies using ABS and PLA filaments; for example, styrene had an emission rate of 0.29-113.10 μg/min, and isopropyl alcohol had an emission rate of 3.55-56.53 μg/min. Emission rates vary depending on the composition of the filament's raw materials, additives (such as dyes and stabilizers), printing conditions (temperature), the printer's condition (whether it has closure), and other factors. Additionally, we reviewed the toxicological concerns associated with hazardous VOC species commonly detected during the ME printing process and estimated cancer and non-cancer risks for users after long-term inhalation exposure. Potential health hazards associated with inhalation exposure to benzene, formaldehyde, acetaldehyde, styrene, and other substances were identified, which were calculated based on concentrations measured in real indoor environments. This study provides valuable insights for future research on the development of ME printing technologies and offers suggestions to reduce VOC emissions to protect users.

Indexed as

3D printing environmentacrylonitrile–butadiene–styreneemission characteristicsFDMmaterial extrusionpolylactic acidtoxicological concern

Identifiers

PMID40278591
PMCPMC12031625

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.