Evidence map›Paper›PMID 40278366›Full record

ArticleMetabolites2025

Association of Serum Uric Acid Levels with Cardiometabolic Factors in Adolescents with Obesity: A Cross-Sectional Study.

Miguel Angel Villasis-Keever, Jessie Nallely Zurita-Cruz, Iris Alejandra Alcaraz-Hurtado, Miguel Klünder-Klünder, Jenny Vilchis-Gil, Ana Laura Romero-Guerra, Ana Laura López-Beltran, Martha Alicia Delgadillo-Ruano

Abstract read
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miguel Angel Villasis-KeeverAnalysis and Synthesis of the Evidence Research Unit, National Medical Center XXI Century, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.ORCID 0000-0002-8566-0811
Jessie Nallely Zurita-CruzFacultad de Medicina Universidad Nacional Autónoma de Mexico, Hospital Infantil de Mexico Federico Gómez, Mexico City 06720, Mexico.
Iris Alejandra Alcaraz-HurtadoDepartment of Pediatric, National Medical Center XXI Century, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.
Miguel Klünder-KlünderEpidemiological Research Unit in Endocrinology and Nutrition, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City 06720, Mexico.ORCID 0000-0003-1914-8366
Jenny Vilchis-GilEpidemiological Research Unit in Endocrinology and Nutrition, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City 06720, Mexico.ORCID 0000-0002-5473-6772
Ana Laura Romero-GuerraDepartment of Pediatric, National Medical Center XXI Century, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.
Ana Laura López-BeltranDepartment of Pediatric Endocrinology, UMAE Pediatric Hospital of the National Medical Center West, IMSS, Guadalajara 44360, Mexico.
Martha Alicia Delgadillo-RuanoDepartment of Pediatric Endocrinology, UMAE Pediatric Hospital of the National Medical Center West, IMSS, Guadalajara 44360, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHigh serum uric acid (SUA) levels are known to be correlated with cardiometabolic factors in adults, but this relationship is less clear in the pediatric population, particularly given the undefined cutoff points for high SUA levels. OBJETIVE: This study aimed to explore the associations between SUA levels and cardiometabolic factors in obese adolescents. MATERIALS AND

methodsWe conducted a cross-sectional study of 391 adolescents aged 10 to 18 years with obesity (BMI > 95th percentile), assessing outcomes such as hypertriglyceridemia, reduced HDL cholesterol, hypertension, hyperglycemia, and insulin resistance. The statistical methods used to compare SUA levels with cardiometabolic factors included the Mann-Whitney U test and the chi-square test.

resultsThe results revealed that the median SUA level was 5.9 mg/dL, with significant differences between the sexes (5.5 mg/dL for girls and 6.1 mg/dL for boys). The highest SUA tertile (≥6.41 mg/dL) was associated with a significantly greater frequency of hyperglycemia and hypertriglyceridemia than the lowest tertile (

conclusionsThe study concluded that higher SUA levels are significantly associated with specific cardiometabolic risks in adolescents with obesity, highlighting the importance of monitoring SUA levels in this population.

Indexed as

adolescentcardiometabolic factorsinsulin resistanceobesityuric acid

Identifiers

PMID40278366
PMCPMC12029226

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.