Evidence map›Paper›PMID 40278354›Full record

ArticleMetabolites2025

Profiling and Discrimination of Euryale Ferox Seeds from Different Processing Methods Using Liquid Chromatography High-Resolution Mass Spectrometry Combined with Molecular Networking and Statistical Analysis.

Xiaoyu Xie, Chuntao Zeng, Ruonan Zhang, Wenting Zhu, Huijie Li, Zhi Huang

Abstract read
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoyu XieDepartment of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Chuntao ZengDepartment of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Ruonan ZhangDepartment of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Wenting ZhuDepartment of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Huijie LiDepartment of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Zhi HuangSchool of Medical Laboratory, Hunan University of Medicine, Jinxi Road No.492, Huaihua 418000, China.ORCID 0000-0003-2599-653X

Funding

Doctoral Start-up Foundation of Jiangxi Province 2004-5252301015Hunan Provincial Natural Science Foundation of China 2023JJ40467Jiangxi Province Traditional Chinese Medicine Science and Technology Program 2024B0292Jiangxi Provincial Special Program for Early-Career Young Scientific and Technological Talents Development 2004-5252403008
6 · The paper itself

Abstract

backgroundEuryale ferox seeds (EFSs) serve both medicinal and culinary purposes. They possess high nutritional value and are rich in polysaccharides, polyphenols, glycolipids, cyclic peptides, and other beneficial components. EFSs are known for their effects in tonifying the kidneys and strengthening essence, invigorating the spleen and alleviating diarrhea, as well as removing dampness and leucorrhea. Processing can alter the chemical composition of EFSs, with different methods yielding varying effects on their chemical makeup and, consequently, their efficacy. However, to date, no studies have systematically investigated the overall chemical composition of EFSs using different processing methods.

methodsIn this study, we employed liquid chromatography high-resolution mass spectrometry (LC-HRMS) to identify the compounds in EFSs by searching databases and Global Natural Products Social Molecular Networking (GNPS), and we comprehensively explored the changes in the chemical composition of EFSs resulting from various processing methods via statistical analysis.

resultsA total of 438 compounds were identified from EFSs, of which 283 were identified through database searches and 155 were identified via GNPS propagation. Statistical analysis revealed 32 and 38 differential compounds in dry-fried Euryale ferox seeds (DFEFSs) and bran-fried Euryale ferox seeds (BFEFSs), respectively. Additionally, we found a significant increase in the lipid content of the fried EFSs.

conclusionsThis study provides valuable data to support the quality evaluation of processed EFSs and contributes to the research on the material basis of their medicinal efficacy.

Indexed as

Euryale ferox seedsliquid chromatography high-resolution mass spectrometrymolecular networkingprocessingstatistical analysis

Identifiers

PMID40278354
PMCPMC12028916

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