Evidence map›Paper›PMID 40278307›Full record

ReviewJournal of personalized medicine2025

Genetic Polymorphisms in Cytochrome P450 Enzymes Involved in Vitamin D Metabolism and the Vitamin D Receptor: Their Clinical Relevance.

Yazun Jarrar, Ghayda' Alhammadin, Su-Jun Lee

Abstract readReview
In one paragraph

Review in Journal of personalized medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  5. Review
  6. Article
  7. Article
  8. Identification and Association ofCurrent issues in molecular biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yazun JarrarDepartment of Basic Medical Sciences, Faculty of Medicine, Al-Balqa Applied University, Al-Salt 19117, Jordan.
Ghayda' AlhammadinDepartment of Pharmaceutical Science, College of Pharmacy, Al-Zaytoonah University of Jordan, Amman 11733, Jordan.ORCID 0009-0006-6501-5432
Su-Jun LeeDepartment of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Inje University, Busan 50834, Republic of Korea.ORCID 0000-0002-3570-0598

Funding

National Research Foundation of Korea funded by Korea 2018R1A5A2021242National Research Foundation of Korea funded by the Korean government NRF-2020R1I1A3073778
6 · The paper itself

Abstract

Individual variations in the active form of vitamin D (Vit.D) arise from a combination of dietary intake, sun exposure, and genetic factors, making it complex and challenging to maintain optimal levels. Among Vit.D-related genes, variations in

Indexed as

cytochrome P450sgenetic variantshuman diseasessingle-nucleotide variantsvitamin Dvitamin D metabolismvitamin D receptor

Identifiers

PMID40278307
PMCPMC12028346

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.