ReviewJournal of cardiovascular development and disease2025
Narrative Review of High-Intensity Interval Training: Positive Impacts on Cardiovascular Health and Disease Prevention.
Review in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Effects of blood flow restriction training on cardiovascular autonomic function in middle-aged and older adults: a meta-analysis.Scientific reports · 2026Pooled it
- Effects of exercise on multiple health outcomes in children and adolescents with overweight or obesity: a meta-analysis of 176 randomized controlled trials and its implications for global obesity prevention.The international journal of behavioral nutrition and physical activity · 2026Pooled it
- Study-level age patterns in cardiometabolic response to high-intensity interval training among adults with overweight or obesity: a systematic review and meta-analysis of randomized controlled trials.Frontiers in physiology · 2026Pooled it
- A meta-analysis of the effects of high-intensity interval training on circulatory system-related indicators in sedentary populations.Frontiers in physiology · 2025Pooled it
- Comparative effects of high-intensity and sprint interval training on cardiorespiratory fitness and body composition: a systematic review with meta-analysis.Frontiers in physiology · 2025Pooled it
- Sports Cardiology in Practice: Exercise as Stressor, Signal, and Therapy.Journal of cardiovascular development and disease · 2026Article
- The Divergent Effects of Nicotinamide Riboside and High-Intensity Exercise Training on Skeletal Muscle Epigenetic Aging.Aging cell · 2026Article
- Weight maintenance after discontinuation of GLP-1 therapies.EClinicalMedicine · 2026Review
- Submaximal Exercise Testing to Dose High-Intensity Interval Training After Stroke: The FAST Randomized Clinical Trial.medRxiv : the preprint server for health sciences · 2026Article
- Agreement Between Reserve Heart Rate, Perceived Exertion and Wint Index During HIIT Using a Low-Cost ANT+ Armband in University Students.Sensors (Basel, Switzerland) · 2026Article
- Mapping Scientific Research on High-Intensity Interval Training (HIIT) in Overweight Populations (2011-2024).Sports (Basel, Switzerland) · 2026Review
- The Acute Effects of High-Intensity Interval Training on Oxidative Stress Markers and Phagocyte Oxidative Burst Activity in Young Professional Athletes and Non-Athlete University Students.Life (Basel, Switzerland) · 2026Article
- Influence of Endurance Training, High-Intensity Interval Training, and Acute Exercise on Left Ventricular Mechanics: A Systematic Review.Journal of clinical medicine · 2025Review
- Mechanisms of exercise in preventing cardiovascular diseases: Insights from gut microbiota characteristics in pathological states of cardiovascular diseases.Reviews in endocrine & metabolic disorders · 2025Review
- High-Intensity Interval Training as Redox Medicine: Targeting Oxidative Stress and Antioxidant Adaptations in Cardiometabolic Disease Cohorts.Antioxidants (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh-intensity interval training (HIIT) has gained recognition for its positive impacts on cardiovascular (CV) health, metabolic outcomes, mental health, and quality of life (QoL). This narrative review aims to comprehensively evaluate the efficacy of HIIT in enhancing CV health and preventing CV disease (CVD).
methodsA comprehensive search of PubMed identified 257 articles, of which 39 studies met predefined inclusion and exclusion criteria for quality assessment. Key metrics evaluated included blood pressure, vascular function, lipid profiles, body composition, and CRF.
resultsHIIT significantly improved vascular function, evidenced by reductions in systolic and diastolic blood pressure and enhanced flow-mediated dilation. Improvements in cardiac function were observed through increased cardiac output and heart rate variability. Additionally, HIIT positively influenced lipid profiles, decreasing low-density lipoprotein and triglycerides while increasing high-density lipoprotein. Significant reductions in body fat and improvements in VO
conclusionsThis review highlights HIIT as an effective and safe exercise modality for improving CV health, metabolic indicators, mental health, and QoL. Future research should focus on developing tailored HIIT protocols to optimize adherence and efficacy across diverse populations, considering variations in age, sex, health status, and underlying medical conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.