Evidence map›Paper›PMID 40278211›Full record

ArticleJournal of cardiovascular development and disease2025

Right Ventricular and Left Atrial Strain Predict Volumetric Response to Cardiac Resynchronization Therapy.

Shing Ching, Jeffrey Ji-Peng Li, Stefanie Maria Werhahn, Rebecca Elisabeth Beyer, Misael Estepa, Christian Stehning, Djawid Hashemi, Natalia Solowjowa, Christoph Klein, Henryk Dreger and 2 more

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shing ChingDeutsches Herzzentrum der Charité-Medical Heart Center of Charité and German Heart Institute, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.
Jeffrey Ji-Peng LiDeutsches Herzzentrum der Charité-Medical Heart Center of Charité and German Heart Institute, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.ORCID 0009-0002-4393-5773
Stefanie Maria WerhahnDeutsches Herzzentrum der Charité-Medical Heart Center of Charité and German Heart Institute, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.
Rebecca Elisabeth BeyerDeutsches Herzzentrum der Charité-Medical Heart Center of Charité and German Heart Institute, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.ORCID 0009-0007-9373-0756
Misael EstepaDeutsches Herzzentrum der Charité-Medical Heart Center of Charité and German Heart Institute, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.
Christian StehningClinical Science, Philips Healthcare, Röntgenstraße 24, 22335 Hamburg, Germany.
Djawid HashemiDeutsches Herzzentrum der Charité-Medical Heart Center of Charité and German Heart Institute, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.
Natalia SolowjowaDeutsches Herzzentrum der Charité-Medical Heart Center of Charité and German Heart Institute, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.
Christoph KleinDeutsches Herzzentrum der Charité-Medical Heart Center of Charité and German Heart Institute, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.
Henryk DregerDeutsches Herzzentrum der Charité-Medical Heart Center of Charité and German Heart Institute, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.ORCID 0000-0003-1909-4329
Sebastian KelleDeutsches Herzzentrum der Charité-Medical Heart Center of Charité and German Heart Institute, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.ORCID 0000-0001-8105-6599
Patrick DoeblinDeutsches Herzzentrum der Charité-Medical Heart Center of Charité and German Heart Institute, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.ORCID 0000-0002-1511-8015

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile left-bundle-branch-block-related contraction patterns as well as echocardiography-derived strain are variably associated with the volumetric response to cardiac resynchronization therapy (CRT), the role of CMR-derived strain parameters is unexplored.

methodsA total of 50 patients receiving CRT implantation were retrospectively analyzed, all of whom had undergone CMR imaging within one year before, and echocardiography within 6 months before and 6-12 months after CRT implantation. We assessed CMR-derived morphological and functional parameters with regard to the echocardiographic response, defined as a reduction in the left ventricular end-systolic volume of ≥15%.

resultsAmong the standard CMR parameters, the indexed right ventricular volumes in end-diastole (RVEDVi) (74.5 ± 19.5 vs. 94.8 ± 30.2 mL/m

conclusionsCMR-derived peak septal circumferential strain and RVEDVi correlated with the echocardiographic volumetric response to CRT at 6-12 months.

Indexed as

cardiac resynchronization therapyleft bundle branch blockright ventriclestrain

Identifiers

PMID40278211
PMCPMC12027857

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.