Evidence map›Paper›PMID 40278195›Full record

ArticleJournal of cardiovascular development and disease2025

Gender Differences in Objective and Subjective Social Isolation and Self-Reported Hypertension in Older Adults.

Tyrone C Hamler, Ann W Nguyen, Harry Owen Taylor, Weidi Qin, Fei Wang

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tyrone C HamlerGraduate School of Social Work, University of Denver, Denver, CO 80210, USA.
Ann W NguyenJack, Joseph and Morton Mandel School of Applied Social Sciences, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID 0000-0002-2592-0773
Harry Owen TaylorFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, ON M5S 1V4, Canada.
Weidi QinSandra Rosenbaum School of Social Work, University of Wisconsin-Madison, Madison, WI 53706, USA.
Fei WangCollege of Social Work, University of Tennessee-Knoxville, Knoxville, TN 37210, USA.ORCID 0000-0003-0860-6317

Funding

Translational and Therapeutics CoreP30AG072959 · NIA · CLEVELAND CLINIC LERNER COM-CWRU · PI Mark J Lowe · 2021 to 2026
$23.9M
Statistical Data Enclave CoreP30AG017266 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Michal Engelman · 1999 to 2026
$17.0M
Research Centers Collaborative Network RenewalU24AG058556 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KRITCHEVSKY, STEPHEN B., LEDERMAN, STEPHANIE · 2018 to 2025
$7.5M
National Institutes of Aging P30AG017266National Institutes of Aging P30AG072959National Institutes of Aging U24AG058556NIA NIH HHS P30 AG017266NIA NIH HHS P30 AG072959NIA NIH HHS U24 AG058556
6 · The paper itself

Abstract

Hypertension is a major public health concern, especially in older adults, and gender differences are a factor in terms of its prevalence. Social connections benefit health, while social isolation is linked to negative outcomes. Prior studies suggest social isolation and connectedness vary by gender, but few have explored this relationship with hypertension. This study examined gender differences in the association between social isolation and hypertension in older adults using data from the National Survey of American Life (1280 adults aged ≥55). Weighted logistic regressions tested gender differences in objective and subjective social isolation and hypertension. Both men and women who were objectively isolated from family and friends, or only friends, were less likely to have hypertension than those not isolated. However, when accounting for subjective isolation, only isolation from family predicted hypertension. Gender moderated this relationship-men isolated from family and friends had a higher likelihood of hypertension, while no such association was found for women. Findings suggest that preventing objective isolation, particularly from family, may help reduce hypertension risk in older adults. This study highlights the need to further investigate social isolation's impact on health and its underlying mechanisms among older adults in the U.S.

Indexed as

health outcomeslonelinesssocial isolationsocial support

Identifiers

PMID40278195
PMCPMC12027778

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.