Evidence map›Paper›PMID 40278182›Full record

ArticleJournal of cardiovascular development and disease2025

Effects of Pulmonary Vein Isolation for Atrial Fibrillation on Skin Sympathetic Nerve Activity in Association with Left Atrial Remodeling.

Yoichiro Nakagawa, Takashi Kusayama, Mayumi Morita, Yuta Nagamori, Kazutaka Takeuchi, Shuhei Iwaisako, Toyonobu Tsuda, Takeshi Kato, Soichiro Usui, Kenji Sakata and 2 more

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yoichiro NakagawaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.ORCID 0000-0003-0266-6829
Takashi KusayamaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.ORCID 0000-0003-0836-1196
Mayumi MoritaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.
Yuta NagamoriDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.
Kazutaka TakeuchiDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.
Shuhei IwaisakoDepartment of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.
Toyonobu TsudaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.
Takeshi KatoDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.
Soichiro UsuiDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.ORCID 0000-0003-1752-8082
Kenji SakataDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.ORCID 0000-0002-6312-8912
Kenshi HayashiDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.ORCID 0000-0002-8219-7729
Masayuki TakamuraDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa City 920-8641, Japan.ORCID 0000-0002-1540-4417

Funding

JSJP KAKENHI 21K16083
6 · The paper itself

Abstract

Pulmonary vein isolation (PVI) is an established treatment for atrial fibrillation (AF). While it is known to affect the autonomic nervous system, the relationship between left atrial (LA) remodeling and PVI-mediated neuromodulation remains unclear. We aimed to assess the neuromodulatory effects of PVI using skin sympathetic nerve activity (SKNA). SKNA was recorded one day before and 2-3 days after PVI in 28 paroxysmal AF (PAF) and 33 persistent AF (PerAF) groups. Baseline low frequency to high frequency (LF/HF) ratio was higher in the PAF group (1.23 [interquartile range {IQR}: 0.79-1.76] vs. 0.74 [IQR: 0.49-1.38],

Indexed as

atrial fibrillationleft atrial remodelingpulmonary vein isolationskin sympathetic nerve activity

Identifiers

PMID40278182
PMCPMC12028141

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.