Evidence map›Paper›PMID 40278173›Full record

ReviewJournal of cardiovascular development and disease2025

The Role of Cardiac Magnetic Resonance in Characterizing Atrial Cardiomyopathy and Guiding Substrate Ablation in Atrial Fibrillation: A Narrative Review.

Jean Pierre Jabbour, Marta Palombi, Michela Bonanni, Andrea Matteucci, Luca Arcari, Nicola Pierucci, Vincenzo Mirco La Fazia, Carlo Lavalle, Marco Valerio Mariani

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jean Pierre JabbourDepartment of Cardiovascular, Respiratory, Nephrological, Anesthesiological and Geriatric Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0003-1758-1078
Marta PalombiDepartment of Cardiovascular, Respiratory, Nephrological, Anesthesiological and Geriatric Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0009-0005-5092-3115
Michela BonanniDepartment of Experimental Medicine, Tor Vergata University, 00133 Rome, Italy.ORCID 0000-0001-8069-592X
Andrea MatteucciDepartment of Experimental Medicine, Tor Vergata University, 00133 Rome, Italy.ORCID 0000-0002-8831-6178
Luca ArcariCardiology Unit, Madre Giuseppina Vannini Hospital, Via di Acqua Bullicante 4, 00177 Rome, Italy.ORCID 0000-0003-1410-6845
Nicola PierucciDepartment of Cardiovascular, Respiratory, Nephrological, Anesthesiological and Geriatric Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0002-5985-4081
Vincenzo Mirco La FaziaDepartment of Experimental Medicine, Tor Vergata University, 00133 Rome, Italy.ORCID 0000-0001-7548-4685
Carlo LavalleDepartment of Internal Clinical, Anesthesiological and Cardiovascular Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.
Marco Valerio MarianiDepartment of Cardiovascular, Respiratory, Nephrological, Anesthesiological and Geriatric Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0002-9480-1209

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac magnetic resonance imaging (MRI) is increasingly recognized as a promising tool for tissue characterization in atrial fibrillation (AF), providing detailed insights into anatomy, fibrosis, and scarring. While MRI cannot directly guide ablation lesions, its ability to identify arrhythmogenic substrates could improve patient stratification and procedural planning. Despite these theoretical advantages, the clinical utility of MRI in guiding substrate-based ablation strategies remains a matter of debate. Methods: Our review evaluates the current evidence supporting the integration of MRI into the workflow of AF ablation. Specifically, we examine findings from randomized trials and prospective studies that have investigated the predictive value of MRI-derived fibrosis quantification for procedural outcomes and arrhythmia recurrence. We aim to assess whether MRI can enhance the personalization of ablation strategies and predict treatment success. Challenges such as variability in imaging protocols, lack of standardization in fibrosis quantification, and limited large-scale validation are also addressed. This review provides a comprehensive overview of the current status and potential of MRI in the evolving field of AF ablation.

Indexed as

atrial cardiomyopathyatrial fibrillationatrial fibrillation ablationcardiac magnetic resonance

Identifiers

PMID40278173
PMCPMC12027483

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.