Evidence map›Paper›PMID 40278168›Full record

ArticleJournal of cardiovascular development and disease2025

Long-Term Outcomes of Mitral Valve Repair Versus Replacement in Patients with Ischemic Mitral Regurgitation: A Retrospective Propensity-Matched Analysis.

Ismail M Elnagar, Rawan Alghamdi, Murtadha H Alawami, Ahmad Alshammari, Abdulmalik A Almedimigh, Monirah A Albabtain, Alaa AlGhamdi, Huda H Ismail, Mostafa A Shalaby, Khaled A Alotaibi and 1 more

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ismail M ElnagarAdult Cardiac Surgery Department, Prince Sultan Cardiac Center, Riyadh 12233, Saudi Arabia.
Rawan AlghamdiAdult Cardiac Surgery Department, Prince Sultan Cardiac Center, Riyadh 12233, Saudi Arabia.
Murtadha H AlawamiAdult Cardiac Surgery Department, Prince Sultan Cardiac Center, Riyadh 12233, Saudi Arabia.
Ahmad AlshammariAdult Cardiac Surgery Department, Prince Sultan Cardiac Center, Riyadh 12233, Saudi Arabia.
Abdulmalik A AlmedimighAdult Cardiac Surgery Department, Prince Sultan Cardiac Center, Riyadh 12233, Saudi Arabia.
Monirah A AlbabtainCardiac Research Department, Prince Sultan Cardiac Center, Riyadh 12233, Saudi Arabia.ORCID 0000-0001-5163-5987
Alaa AlGhamdiHealth Research Center, Ministry of Defense Healthcare Services, Riyadh 12426, Saudi Arabia.
Huda H IsmailAdult Cardiac Surgery Department, Prince Sultan Cardiac Center, Riyadh 12233, Saudi Arabia.
Mostafa A ShalabyAdult Cardiac Surgery Department, Prince Sultan Cardiac Center, Riyadh 12233, Saudi Arabia.
Khaled A AlotaibiAdult Cardiac Surgery Department, Prince Sultan Cardiac Center, Riyadh 12233, Saudi Arabia.
Amr A ArafatAdult Cardiac Surgery Department, Prince Sultan Cardiac Center, Riyadh 12233, Saudi Arabia.ORCID 0000-0003-0951-7287

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal surgical management of ischemic mitral regurgitation (IMR)-mitral valve repair (MVr) versus mitral valve replacement (MVR)-remains controversial, with limited evidence on long-term outcomes. This study aimed to compare the outcomes of MVr and MVR in patients with IMR, focusing on survival and recurrence of mitral regurgitation. Additionally, survival was compared based on preoperative characteristics.

methodsA retrospective cohort analysis was conducted at a tertiary referral center and included 759 patients who underwent surgery for IMR between 2009 and 2021. Propensity score matching identified 140 matched pairs. The outcomes assessed included hospital mortality, long-term survival, recurrence of mitral regurgitation, mitral valve reintervention rates, and echocardiographic changes over time.

resultsIn the matched cohort, no significant differences were observed in hospital mortality (10% for MVr vs. 10.7% for MVR,

conclusionsMVr and MVR for IMR yielded comparable survival rates, but MVr was associated with a higher risk of recurrent MR. The efficacy of both surgical approaches across diverse patient populations was comparable, reinforcing the need for individualized decision-making based on other clinical and anatomical considerations.

Indexed as

ischemic mitral regurgitationleft ventricular dimensionsleft ventricular ejection fractionmitral valve repairmitral valve replacementreinterventionsurvival

Identifiers

PMID40278168
PMCPMC12027820

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.