Evidence map›Paper›PMID 40278117›Full record

ReviewJournal of fungi (Basel, Switzerland)2025

Mycobiota and Antifungal Antibodies as Emerging Targets for the Diagnosis and Prognosis of Human Diseases.

Eguzkiñe Diez-Martin, Leidi Hernandez-Suarez, Egoitz Astigarraga, Andoni Ramirez-Garcia, Gabriel Barreda-Gómez

Abstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eguzkiñe Diez-MartinResearch and Development Department, IMG Pharma Biotech S.L., 48170 Zamudio, Spain.ORCID 0000-0002-7151-1639
Leidi Hernandez-SuarezResearch and Development Department, IMG Pharma Biotech S.L., 48170 Zamudio, Spain.ORCID 0009-0005-5092-3625
Egoitz AstigarragaResearch and Development Department, IMG Pharma Biotech S.L., 48170 Zamudio, Spain.ORCID 0000-0002-0338-5554
Andoni Ramirez-GarciaDepartment of Immunology, Microbiology and Parasitology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.ORCID 0000-0003-2696-162X
Gabriel Barreda-GómezResearch and Development Department, IMG Pharma Biotech S.L., 48170 Zamudio, Spain.ORCID 0000-0002-8330-1567

Funding

Basque Government Department of Economic Development, Sustainability and Environment Bikaintek program 004-B2/2022Basque Government Department of Economic Development, Sustainability and Environment Bikaintek program 006-B2/2021University of the Basque Country, UPV/EHU PIFIND21/02
6 · The paper itself

Abstract

The human body is colonized by diverse microorganisms, with bacteria being the most extensively studied. However, fungi, collectively known as "the mycobiota," are increasingly recognized as integral components of the microbiota, inhabiting nearly all mucosal surfaces. Commensal fungi influence host immunity similarly to bacteria and contribute to other essential functions, including metabolism. This emerging understanding positions fungi as potential biomarkers for the diagnosis and prognosis of various diseases. In this review, we explore the dual roles of fungi as both commensals and pathogens, and the potential of antifungal antibodies to serve as diagnostic and prognostic tools, especially in chronic immune-inflammatory non-communicable diseases, including inflammatory bowel disease, rheumatoid arthritis, multiple sclerosis, and neurodegenerative disorders. Finally, we address current challenges and outline future perspectives for leveraging fungal biomarkers in clinical practice.

Indexed as

antifungal antibodiescommensal fungimycobiotapathogenic fungi

Identifiers

PMID40278117
PMCPMC12028713

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.