Evidence map›Paper›PMID 40278106›Full record

ArticleJournal of fungi (Basel, Switzerland)2025

Use of a 3D Model with Reconstructed Human Epidermis Infected with Fungi and Covered with a Bovine Nail to Simulate Onychomycosis and to Evaluate the Effects of Antifungal Agents.

Francesca Giulia Urso, Salvatore Del Prete, Christelle Foucher, Martina Barberis, Francesco Carriero, Amandine Bart

Abstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Francesca Giulia UrsoThe Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, University of Copenhagen, Norre Alle 14, 2200 København N, Denmark.ORCID 0009-0001-6702-1194
Salvatore Del PreteService Biotech, Via Croce Rossa, 23, 80131 Napoli, Italy.ORCID 0000-0001-6004-7781
Christelle FoucherUrgo Research Innovation & Development, 42 Rue de Longvic, 21300 Chenôve, France.
Martina BarberisVitroscreen, Via Mosè Bianchi, 103, 20149 Milan, Italy.
Francesco CarrieroVitroscreen, Via Mosè Bianchi, 103, 20149 Milan, Italy.
Amandine BartUrgo Research Innovation & Development, 42 Rue de Longvic, 21300 Chenôve, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An in vitro 3D model using fungus colonized Reconstructed Human Epidermis (RHE) represents an effective preclinical model to simulate the pathological conditions of onychomycosis. We evaluated the suitability of this 3D onychomycosis model and use it to assess the effects of topical products on fungus growth and nail structure. Five sets of differentiated RHE were colonized with

Indexed as

antifungal agentsfungiin vitro modelonychomycosisreconstructed human epidermisScanning Electron MicroscopyTrichophyton rubrum

Identifiers

PMID40278106
PMCPMC12028449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.