Evidence map›Paper›PMID 40277979›Full record

ArticleMembranes2025

The Nexus Between Sperm Membrane Integrity, Sperm Motility, and DNA Fragmentation.

Alfredo Góngora, Stephen Johnston, Pablo Contreras, Carmen López-Fernández, Jaime Gosálvez

Abstract read
In one paragraph

Article in Membranes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Seminal Analysis and Testicular RNA Sequencing of a Ram with Low Fertility.Animals : an open access journal from MDPI · 2026
    Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alfredo GóngoraCentro de Fertilidad Humana en Mexico DF, Ciudad de México 06760, Mexico.
Stephen JohnstonSchool of Environment, University of Queensland, Gatton, QLD 4343, Australia.ORCID 0000-0002-0290-5458
Pablo ContrerasHalotech DNA, Parque Cientifico de Madrid, 28049 Madrid, Spain.ORCID 0000-0003-3067-915X
Carmen López-FernándezHalotech DNA, Parque Cientifico de Madrid, 28049 Madrid, Spain.
Jaime GosálvezDepartment of Biology, Universidad Autónoma de Madrid, 28049 Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the interrelationships between sperm plasma membrane integrity, motility, and DNA fragmentation (SDF) to provide a more holistic understanding of male fertility. A total of 1159 ejaculates were analyzed for sperm membrane integrity (% dead spermatozoa), motility (% immotile spermatozoa), and SDF (% sperm with fragmented DNA). The statistical methods included non-parametric correlation analysis and artificial intelligence (AI)-generated cluster analysis to identify patterns based on these three parameters. The results showed a moderate correlation (ρ = 0.65;

Indexed as

cluster analysisintegrated sperm qualitysperm DNA fragmentationsperm motilitysperm plasma membrane integrity

Identifiers

PMID40277979
PMCPMC12028733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.