Lignin-Mediated Dual Conductive Hydrogels with High Conductivity, Antibacterial Activity and Biocompatibility for Chronic Wound Repair.

Jianhong Lin, Mengyao Chen, Wei Zhao, Shengyu Zhang, Jialin Liu, Yang Zhou, Lei Jiang, Jiantao Zhang

Abstract read

In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

From structural complexity to circular applications: a comparative review of the enzymatic degradation of polydopamine, tannins, lignins, and melanins.RSC advances · 2026
Review
Black phosphorus in theragenerative medicine: a multi-organ perspective on disease modulation and tissue repair.Bioactive materials · 2026
Review
Comparative Biofunctionality Assessment of Lignin and Lignin/Chitosan Nanoparticles: Impact of Chitosan Co-Assembly on Cytotoxicity, Cytocompatibility, Radical-Scavenging Activity, and Antimicrobial Performance.Pharmaceutics · 2026
Article
Nanozymes based on functionalized iridium oxide-modified gold nanoparticles for combination therapy.RSC advances · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jianhong LinLaboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.

Mengyao ChenLaboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.

Wei ZhaoLaboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.

Shengyu ZhangLaboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.

Jialin LiuLaboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.

Yang ZhouLaboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.

Lei JiangLaboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.

Jiantao ZhangLaboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.

Funding

China Postdoctoral Science Foundation 2023M733599Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China HDMZ25H300005Ningbo Science and Technology Bureau 2023J370Ningbo Science and Technology Bureau 2024QL031

6 · The paper itself

Abstract

In recent years, conductive polymer hydrogels based on polypyrrole (PPy) combined with electrical stimulation (ES) have emerged as a promising approach for chronic wound repair. However, in practical applications, PPy often exhibits limitations such as poor water dispersion, weak inherent conductivity and a lack of biological functionality. To address these challenges, this study proposes an innovative design of a conductive hydrogel that employs a natural biopolymer, lignin sulfonate (Lgs), as both a dispersant and dopant for PPy, while incorporating silver nanoparticles (Ag NPs) to confer the hydrogel antibacterial properties. The results showed that the water dispersion of PPy was significantly improved, and the conductivity of the hydrogel was as high as 2.82 ± 0.04 mS/cm through the double conduction mechanism of PPy and Ag NPs. The hydrogel exhibited antibacterial activity against Escherichia coli (

Indexed as

chronic woundconductive hydrogelslignin sulfonatepolypyrrolesilver nanoparticles

Identifiers

PMID40277720

DOI10.3390/gels11040283

PMCPMC12026575

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.