Evidence map›Paper›PMID 40277580›Full record

ArticleAudiology research2025

Using Machine Learning for Analysis of Wideband Acoustic Immittance and Assessment of Middle Ear Function in Infants.

Shan Peng, Yukun Zhao, Xinyi Yao, Huilin Yin, Bei Ma, Ke Liu, Gang Li, Yang Cao

Abstract read
In one paragraph

Article in Audiology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shan PengDepartment of Audiology and Speech Language Pathology, Department of Otorhinolaryngology-Head & Neck Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.
Yukun ZhaoKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Wangjiang Road 29, Chengdu 610065, China.
Xinyi YaoDepartment of Audiology and Speech Language Pathology, Department of Otorhinolaryngology-Head & Neck Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.
Huilin YinDepartment of Audiology and Speech Language Pathology, Department of Otorhinolaryngology-Head & Neck Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.
Bei MaHealth Examination Center, Sichuan Electric Power Hospital, Chengdu 610011, China.
Ke LiuKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Wangjiang Road 29, Chengdu 610065, China.ORCID 0000-0002-4683-9325
Gang LiDepartment of Audiology and Speech Language Pathology, Department of Otorhinolaryngology-Head & Neck Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.
Yang CaoKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Wangjiang Road 29, Chengdu 610065, China.

Funding

Science and Technology department of Sichuan Province 2021YFS0220
6 · The paper itself

Abstract

objectivesEvaluating middle ear function is essential for interpreting screening results and prioritizing diagnostic referrals for infants with hearing impairments. Wideband Acoustic Immittance (WAI) technology offers a comprehensive approach by utilizing sound stimuli across various frequencies, providing a deeper understanding of ear physiology. However, current clinical practices often restrict WAI data analysis to peak information at specific frequencies, limiting its comprehensiveness.

designIn this study, we developed five machine learning models-feedforward neural network, convolutional neural network, kernel density estimation, random forest, and support vector machine-to extract features from wideband acoustic immittance data collected from newborns aged 2-6 months. These models were trained to predict and assess the normalcy of middle ear function in the samples.

resultsThe integrated machine learning models achieved an average accuracy exceeding 90% in the test set, with various classification performance metrics (accuracy, precision, recall, F1 score, MCC) surpassing 0.8. Furthermore, we developed a program based on ML models with an interactive GUI interface. The software is available for free download.

conclusionsThis study showcases the capability to automatically diagnose middle ear function in infants based on WAI data. While not intended for diagnosing specific pathologies, the approach provides valuable insights to guide follow-up testing and clinical decision-making, supporting the early identification and management of auditory conditions in newborns.

Indexed as

hearing of infantsmachine learningmiddle ear functionwideband acoustic immittance

Identifiers

PMID40277580
PMCPMC12023930

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.