Evidence map›Paper›PMID 40277574›Full record

ArticleBiosensors2025

Distinct Neural Activities in Hippocampal Subregions Revealed Using a High-Performance Wireless Microsystem with PtNPs/PEDOT:PSS-Enhanced Microelectrode Arrays.

Peiyao Jiao, Qianli Jia, Shuqi Li, Jin Shan, Wei Xu, Yu Wang, Yu Liu, Mingchuan Wang, Yilin Song, Yulian Zhang and 3 more

Abstract read
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Peiyao JiaoState Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.
Qianli JiaState Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.
Shuqi LiState Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.
Jin ShanState Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.
Wei XuState Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.
Yu WangState Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.
Yu LiuState Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.
Mingchuan WangState Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.
Yilin SongState Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.
Yulian ZhangDepartment of Neurosurgery, China-Japan Friendship Hospital, Beijing 100029, China.ORCID 0000-0003-0752-1522
Yanbing YuDepartment of Neurosurgery, China-Japan Friendship Hospital, Beijing 100029, China.
Mixia WangState Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.
Xinxia CaiState Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.ORCID 0000-0001-5997-7252

Funding

Major Program of Scientific and Technical Innovation 2030 2021ZD02016030the National Key Research and Development Program of China 2022YFB3205602the National Key Research and Development Program of China 2022YFC2402501the National Key Research and Development Program of China 2022YFC2402503the National Natural Science Foundation of China 61960206012the National Natural Science Foundation of China 62121003the National Natural Science Foundation of China 62171434the National Natural Science Foundation of China 62333020the National Natural Science Foundation of China T2293730the National Natural Science Foundation of China T2293731the Scientific Instrument Developing Project of the Chinese Academy of Sciences PTYQ2024BJ0009
6 · The paper itself

Abstract

Wireless microsystems for neural signal recording have emerged as a solution to overcome the limitations of tethered systems, which restrict the mobility of subjects and introduce noise interference. However, existing microsystems often face data throughput, signal processing, and long-distance wireless transmission challenges. This study presents a high-performance wireless microsystem capable of 32-channel, 30 kHz real-time recording, featuring Field Programmable Gate Array (FPGA)-based signal processing to reduce transmission load. The microsystem is integrated with platinum nanoparticles/poly (3,4-ethylenedioxythiophene) polystyrene sulfonate-enhanced microelectrode arrays for improved signal quality. A custom NeuroWireless platform was developed for seamless data reception and storage. Experimental validation in rats demonstrated the microsystem's ability to detect spikes and local field potentials from the hippocampal CA1 and CA2 subregions. Comparative analysis of the neural signals revealed distinct activity patterns between these subregions. The wireless microsystem achieves high accuracy and throughput over distances up to 30 m, demonstrating its resilience and potential for neuroscience research. This work provides a compact, adaptable solution for multi-channel neural signal detection and offers a foundation for future applications in brain-computer interfaces.

Indexed as

Biosensing TechniquesHippocampusWireless TechnologyAnimalsBridged Bicyclo Compounds, HeterocyclicMaleMetal NanoparticlesMicroelectrodesPlatinumPolymersPolystyrenesRatsRats, Sprague-DawleyBridged Bicyclo Compounds, HeterocyclicPlatinumPolymersPolystyrenesFPGAhippocampusneural signal processingwireless microsystem

Identifiers

PMID40277574
PMCPMC12026308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.