Nanoparticulate Copper Cluster-Mediated Biosensing of Cardiac Biomolecular Markers.

Lakshmi V Nair, Jarred Wheeler, Yaelyn Ha, Kimberly M Jones, Jesse Jones, Vinoy Thomas

Abstract read

In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lakshmi V NairDepartment of Mechanical and Materials Engineering, School of Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Jarred WheelerDepartment of Mechanical and Materials Engineering, School of Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Yaelyn HaDepartment of Mechanical and Materials Engineering, School of Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0009-0003-6027-8653

Kimberly M JonesDepartment of Mechanical and Materials Engineering, School of Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Jesse JonesDepartment of Neurosurgery, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Vinoy ThomasDepartment of Mechanical and Materials Engineering, School of Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-1191-3353

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Being a leading cause of death, heart diseases across the globe need special attention to enable early diagnosis. Metal nanoparticle-mediated biosensors are useful clinical tools for the early detection of bio-analytes. The size-dependent surface plasmon resonance (SPR) of metal nanoparticles can be effectively utilized for the same purpose. The early detection of heart diseases can be evaluated by monitoring the troponin level. A copper nanoparticle-mediated troponin biosensor was developed through antibody conjugation for troponin I and troponin T. The copper nanosensor shows a concentration-dependent SPR change towards troponin T and troponin I.

Indexed as

Biosensing TechniquesCopperMetal NanoparticlesTroponin ITroponin TBiomarkersHumansSurface Plasmon ResonanceBiomarkersCopperTroponin ITroponin Tbiosensorcardiac biomarkercoppertroponin

Identifiers

PMID40277550

DOI10.3390/bios15040237

PMCPMC12025221

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.