Evidence map›Paper›PMID 40277540›Full record

ArticleBiosensors2025

Ternary-Emission Molecularly Imprinted Ratiometric Fluorescence Sensor and Kit for the Rapid and Visual Detection of Enrofloxacin.

Siwu Liu, Jingyi Yan, Dani Sun, Siyuan Peng, Jinhua Li, Huaying Fan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. ZIF-8-Confined and APTES-Passivated CsPbBrFoods (Basel, Switzerland) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Siwu LiuSchool of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, China.
Jingyi YanSchool of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, China.
Dani SunCoastal Zone Ecological Environment Monitoring Technology and Equipment Shandong Engineering Research Center, Shandong Key Laboratory of Coastal Environmental Processes, Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
Siyuan PengCoastal Zone Ecological Environment Monitoring Technology and Equipment Shandong Engineering Research Center, Shandong Key Laboratory of Coastal Environmental Processes, Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
Jinhua LiCoastal Zone Ecological Environment Monitoring Technology and Equipment Shandong Engineering Research Center, Shandong Key Laboratory of Coastal Environmental Processes, Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.ORCID 0000-0002-6069-9795
Huaying FanSchool of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, China.ORCID 0000-0001-6245-7450

Funding

National Natural Science Foundation of China 22176210
6 · The paper itself

Abstract

In this study, a RGB based ternary-emission molecularly imprinted ratiometric fluorescence (MI-RFL) sensor was facilely constructed by using a post-imprinting mixing strategy for the sensitive detection of enrofloxacin (ENR). Upon excitation at 365 nm, the MI-RFL sensor exhibited significant emission peaks at 450, 550, and 620 nm. As the ENR concentration increased, the blue fluorescence generated by ENR in the sensing system gradually intensified, while the red and green fluorescence emitted by the quantum dots in the molecularly imprinted polymers (MIPs) was significantly quenched. Sensing conditions were systematically investigated, including the excitation wavelength, mixing ratio of red/green MIPs, the pH of the buffer solution, and the reaction time. Under the optimal conditions, the developed sensor showed a good linear relationship within the range of 0.25-4 ppm along with obvious color change, with a low detection limit of 0.134 ppm. High selectivity was also attained with an imprinting factor up to 11.65. When applied to real samples of seawater and seafood, the sensor showed good recovery rates of 94.3-126.4% and accuracy with a relative standard deviation of less than 3.97%. Furthermore, the sensor-based kit was easily fabricated and, thus, naked-eye detection of ENR was realized onsite. This study can provide a universal approach for the rapid and visual detection of ENR in complicated matrices.

Indexed as

Biosensing TechniquesEnrofloxacinFluoroquinolonesMolecular ImprintingFluorescenceLimit of DetectionMolecularly Imprinted PolymersQuantum DotsSpectrometry, FluorescenceEnrofloxacinFluoroquinolonesMolecularly Imprinted Polymersenrofloxacinkitmolecular imprintingpost-imprinting mixingratiometric fluorescence

Identifiers

PMID40277540
PMCPMC12024939

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.