Evidence map›Paper›PMID 40277520›Full record

ReviewBiosensors2025

A Review of Readout Circuit Schemes Using Silicon Nanowire Ion-Sensitive Field-Effect Transistors for pH-Sensing Applications.

Jungho Joo, Hyunsun Mo, Seungguk Kim, Seonho Shin, Ickhyun Song, Dae Hwan Kim

Abstract readReview
In one paragraph

Review in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jungho JooDepartment of Intelligent Semiconductor and Display Engineering, Kookmin University, Seoul 02707, Republic of Korea.
Hyunsun MoSchool of Electrical Engineering, Kookmin University, Seoul 02707, Republic of Korea.
Seungguk KimSchool of Electrical Engineering, Kookmin University, Seoul 02707, Republic of Korea.
Seonho ShinDepartment of Artificial Intelligence Semiconductor Engineering, Hanyang University, Seoul 04763, Republic of Korea.ORCID 0009-0001-2402-4758
Ickhyun SongDepartment of Electronic Engineering, Hanyang University, Seoul 04763, Republic of Korea.ORCID 0000-0002-7669-9853
Dae Hwan KimSchool of Electrical Engineering, Kookmin University, Seoul 02707, Republic of Korea.ORCID 0000-0003-2567-4012

Funding

National Research Foundation of Korea (NRF) RS-2023-00208661, 2019M3F3A1A02071845, RS-2024-00404624, 2022M3I7A078936
6 · The paper itself

Abstract

This paper reviews various design approaches for sensing schemes that utilize silicon nanowire (SiNW) ion-sensitive field-effect transistors (ISFETs) for pH-sensing applications. SiNW ISFETs offer advantageous characteristics, including a high surface-to-volume ratio, fast response time, and suitability for integration with complementary metal oxide semiconductor (CMOS) technology. This review focuses on SiNW ISFET-based biosensors in three key aspects: (1) major fabrication processes and device structures; (2) theoretical analysis of key performance parameters in readout circuits such as sensitivity, linearity, noise immunity, and output range in different system configurations; and (3) an overview of existing readout circuits with quantitative evaluations of N-type and P-type current-mirror-based circuits, highlighting their strengths and limitations. Finally, this paper proposes a modified N-type readout scheme integrating an operational amplifier with a negative feedback network to overcome the low sensitivity of conventional N-type circuits. This design enhances gain control, linearity, and noise immunity while maintaining stability. These advancements are expected to contribute to the advancement of the current state-of-the-art SiNW ISFET-based readout circuits.

Indexed as

Biosensing TechniquesNanowiresSiliconTransistors, ElectronicEquipment DesignHydrogen-Ion ConcentrationSemiconductorsSiliconion-sensitive field-effect transistor (ISFET)N-type/P-type circuitpH sensorreadout schemesilicon nanowire (SiNW)

Identifiers

PMID40277520
PMCPMC12024945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.