Evidence map›Paper›PMID 40277406›Full record

ArticleMicrobiology spectrum2025

Characterizing the impact of podophyllotoxin on pulmonary toxicity and gut-lung microbiota interactions in SD rats based on TEC concept.

Min Wang, Xiao Ma, Junjie He, Jiaxing Sun, Feng Cai, Chuanxin Liu, Jiajia Duan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Min WangDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, , Luoyang, China.
Xiao MaDepartment of Clinical Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, , Luoyang, China.
Junjie HeSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Jiaxing SunDepartment of Clinical Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, , Luoyang, China.
Feng CaiDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Chuanxin LiuHenan Key Laboratory of Rare Diseases, Endocrinology and Metabolism Center, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, , Luoyang, China.ORCID 0000-0002-4492-6150
Jiajia DuanDepartment of Clinical Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, , Luoyang, China.ORCID 0000-0002-7587-1789

Funding

Henan Medical Science and Technique Foundation SBGJ202303042National Natural Science Foundation of China 82204938National Natural Science Foundation of China 82400015National Natural Science Foundation of China 82404774
6 · The paper itself

Abstract

Podophyllotoxin (PPT), an extract from the traditional medicinal plant IMPORTANCE: PPT, derived from the medicinal plant

Indexed as

Gastrointestinal MicrobiomeLungPodophyllotoxinAnimalsBacteriaBronchoalveolar Lavage FluidCytokinesMaleRatsRats, Sprague-DawleyRNA, Ribosomal, 16SCytokinesPodophyllotoxinRNA, Ribosomal, 16Sgut microbiotametabolomemicrobiota-gut-lung axispodophyllotoxinpulmonary toxicity

Identifiers

PMID40277406
PMCPMC12131824

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.