Evidence map›Paper›PMID 40277348›Full record

ArticleStatistics in medicine2025

Improving Efficiency and Robustness of the Prognostic Accuracy of Biomarkers With Partial Incomplete Failure-Time Data and Auxiliary Outcome: Application to Prostate Cancer Active Surveillance Study.

Yunro Chung, Tianxi Cai, Lisa Newcomb, Daniel W Lin, Yingye Zheng

Abstract read
In one paragraph

Article in Statistics in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yunro ChungCollege of Health Solutions, Arizona State University, Phoenix, AZ, USA.ORCID https://orcid.org/0000-0001-9125-9277
Tianxi CaiDepartment of Biostatistics, Harvard University, Boston, MA, USA.
Lisa NewcombDepartment of Urology, University of Washington, Seattle, WA, USA.
Daniel W LinDepartment of Urology, University of Washington, Seattle, WA, USA.
Yingye ZhengDepartment of Biostatistics, Fred Hutchinson Cancer Center, Seattle, WA, USA.

Funding

The Early Detection Research Network: Data Management and Coordinating CenterU24CA086368 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI RUTH D ETZIONI, Ziding Feng · 2010 to 2026
$75.7M
EDRN--DATA MANAGEMENT AND COORDINATING CENTERU01CA086368 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI FENG, ZIDING · 2000 to 2010
$16.9M
Statistical Methods for Optimizing Personalized Treatment SelectionR01HL089778 · NHLBI · STANFORD UNIVERSITY · PI LU TIAN · 2008 to 2026
$4.8M
Statistical Methods for Prospective Evaluation of BiomarkersR01CA236558 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ZHENG, YINGYE · 2019 to 2024
$1.9M
Evaluation of commercially available prostate cancer assays to accelerate novel applications in active surveillanceUH3CA234196 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LIN, DANIEL W., ZHENG, YINGYE · 2019 to 2021
$1.0M
NCI NIH HHS R01 CA236558NCI NIH HHS U01 CA086368NCI NIH HHS U24 CA086368NCI NIH HHS UH3 CA234196NHLBI NIH HHS R01 HL089778NIH HHS R01 CA236558NIH HHS R01 HL089778NIH HHS U01 CA86368NIH HHS UH3CA234196
6 · The paper itself

Abstract

When novel biomarkers are developed for the clinical management of patients diagnosed with cancer, it is critical to quantify the accuracy of a biomarker-based decision tool. The evaluation can be challenging when the definite outcome

Indexed as

Biomarkers, TumorProstatic NeoplasmsWatchful WaitingComputer SimulationDisease ProgressionHumansMaleModels, StatisticalPrognosisProstate-Specific AntigenBiomarkers, TumorProstate-Specific Antigeninformative censoringmis‐measured outcomemissing dataprognostic accuracyreceiver operating characteristics curvesurvival analysis

Identifiers

PMID40277348
PMCPMC12614110

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.