Evidence map›Paper›PMID 40277275›Full record

ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2025

G Protein-Coupled Receptor Signal Intersection at the Primary Cilium.

Christina E Wang, Stacey K Ogden

Abstract readReview
In one paragraph

Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. The nociceptor primary cilium.Brain : a journal of neurology · 2026
    Review
  3. Article
  4. Design principles of ciliary signaling.Journal of cell science · 2025
    Review
  5. When G Protein-Coupled Receptor Signaling Meets the Primary Cilium: Implications for Sonic Hedgehog Signaling.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christina E WangDepartment of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Stacey K OgdenDepartment of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID https://orcid.org/0000-0001-8991-3065

Funding

Mechanisms of Sonic Hedgehog Signal TransductionR35GM122546 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Stacey Kathryn Ogden · 2017 to 2026
$4.8M
ALSAC of St. Jude Children's Research HospitalNIGMS NIH HHS R35 GM122546NIGMS NIH HHS R35GM122546
6 · The paper itself

Abstract

Primary cilia are singular projections that extend from the surface of most vertebrate cell types. The surface area of the primary cilium (PC) is estimated to represent only 1/100

Indexed as

CiliaReceptors, G-Protein-CoupledSignal TransductionAnimalsHedgehog ProteinsHumansHedgehog ProteinsReceptors, G-Protein-CoupledGPCRsprimary ciliasignal crosstalkSonic Hedgehog

Identifiers

PMID40277275
PMCPMC13244655

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.