ArticleInternational endodontic journal2025
Effect of light-cured pulp capping materials on human dental pulp cells in vitro.
Article in International endodontic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed.
- Comparison of five different Light-Cured Pulp Capping Materials to a Hydraulic Calcium Silicate Cement: A Long-Term Physicochemical Study.International dental journal · 2026Article
- Clinical and radiographic outcomes of partial pulpotomy procedure in primary molars utilising different capping materials and different sealing methods: a randomised clinical trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- In Vitro Evaluation of Novel Resin-Modified Calcium Silicate Cements for Minimally Invasive Vital Pulp Therapy.International dental journal · 2026Article
- Next-Gen Restorative Materials to Revolutionise Smiles.Bioengineering (Basel, Switzerland) · 2026Review
- Clinical and Radiographic Outcomes of Vital Pulp Therapy Using Resin-Modified Versus Conventional Calcium Silicate-Based Materials: A Systematic Review and Meta-Analysis.Journal of functional biomaterials · 2026Review
- Physicochemical properties and periodontal ligament stem cell response to NeoMTA 2.Clinical oral investigations · 2025Article
- Effect of light-cured pulp capping materials on human dental pulp cells in vitro.International endodontic journal · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
aimGold standard as material in vital pulp therapy (VPT) is hydraulic calcium silicate cements (HCSC). To circumvent their prolonged setting time, light-cured pulp capping materials containing calcium silicate or calcium hydroxide powder are available. Although their positive biological properties are advertised, the data regarding the biocompatibility of light-cured pulp capping materials (LCPCM) is inconclusive. This in vitro study compared the biocompatibility of five LCPCM containing calcium silicate (TheraCal LC, ReviCal, MTA PulpCap, Pulprotec MTA) or calcium hydroxide (Calcimol LC) with that of the HCSC Biodentine.
methodsOf each material, 226 cylindrical specimens (51.472 mm
resultsCompared to Biodentine, hDPC showed significantly lower cell viability when in contact with LCPCM (p < 0.05). Further, an inhibition zone around the test bodies or an altered cell morphology was observed. Biodentine showed almost no negative effects on cell viability or cell morphology. In contact with Biodentine, hDPC mineralise with and without mineralisation induction conditions. Among the LCPCM, mineralisation was only detectable under induction conditions with ReViCal and MTA PulpCap. In addition, Biodentine released significantly more calcium ions than the LCPCM (p < 0.05).
conclusionIn this in vitro study, LCPCM showed cytotoxic effects on hDPC and were hardly able to induce cell mineralisation. Biodentine showed little negative effects on cell viability, induced cell mineralisation and released more calcium than LCPCM. Biodentine is significantly superior to LCPCM in terms of biocompatibility and mineralisation induction capacity.
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