Evidence map›Paper›PMID 40277058›Full record

ArticleCurrent pharmaceutical biotechnology2025

Potential Pharmacological Ability of a Novel Marine Polysaccharide Extracted from Tunisian Green Algae

Marwa Kraiem, Malek Eleroui, Zakaria Boujhoud, Marwa Ajala, Marwa Bouhamed, Abderraouf Hilali, Hatem Kallel, Ibtissem Ben Amara

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Article in Current pharmaceutical biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Marwa KraiemLaboratory of Medicinal and Environment Chemistry, Higher Institute of Biotechnology, University of SFAX, PB 261, Sfax 30 0 0, Tunisia.
Malek ElerouiLaboratory of Medicinal and Environment Chemistry, Higher Institute of Biotechnology, University of SFAX, PB 261, Sfax 30 0 0, Tunisia.
Zakaria BoujhoudLaboratory of Health and Food, Faculty of Science and Technology University of Hassen 1st Settat, Morocco.
Marwa AjalaLaboratory of Medicinal and Environment Chemistry, Higher Institute of Biotechnology, University of SFAX, PB 261, Sfax 30 0 0, Tunisia.
Marwa BouhamedLaboratory of Anatomopathology, CHU Habib Bourguiba, University of Sfax, 3029 Sfax, Tunisia.
Abderraouf HilaliLaboratory of Health and Food, Faculty of Science and Technology University of Hassen 1st Settat, Morocco.
Hatem KallelIntensive Care Unit, Cayenne General Hospital, French Guiana.
Ibtissem Ben AmaraLaboratory of Medicinal and Environment Chemistry, Higher Institute of Biotechnology, University of SFAX, PB 261, Sfax 30 0 0, Tunisia.

Funding

Tunisian-Moroccan project 20PRD16
6 · The paper itself

Abstract

backgroundBacterial infection and oxidative stress generation are significant obstacles to dermal wound healing. The present study undertakes the isolation of a sulfated polysaccharide from the Tunisian green algal

methodsThe polysaccharide PCA was structurally characterized using Fourier Transformed Infrared (FT-IR), and monosaccharide analysis was carried out by HPLC-FID X-ray diffraction (XRD) and Scanning Electron Microscopy (SEM). The antioxidant potential of polysaccharides extracted from the

resultsFT-IR spectra revealed the characteristic bands of polysaccharides. HPLC-FID revealed a heteropolysaccharide composed of arabinose, glucose, glucuronic acid, and galactose units. Indeed, the X-ray diffraction revealed a semi-crystalline structure of PCA. The obtained data showed a strong antioxidant capacity and an interesting antibacterial activity against four-gram negative bacteria

conclusionThe present study highlights the promising pharmacological effects of PCA, suggesting its potential application in wound dressings due to its robust antioxidant, antibacterial, and wound-healing properties.

Indexed as

Anti-Bacterial AgentsAntioxidantsChlorophytaPolysaccharidesWound HealingAnimalsGram-Negative BacteriaMaleRatsRats, WistarSeaweedSkinTunisiaAnti-Bacterial AgentsAntioxidantsPolysaccharidesantibacterial activityantioxidant activityChaetomorpha aereaPCAsulfated polysaccharidewound healing.

Identifiers

PMID40277058

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