Evidence map›Paper›PMID 40277048›Full record

ArticleCurrent aging science2026

Subtle Intrusion: Minimal Serous Uterine Carcinoma in an Asymptomatic Postmenopausal Patient-A Case Report.

Naina Kumar, Seetu Palo, Ashutosh Rath, Mishu Mangla, Pooja Rathod

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Article in Current aging science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Naina KumarDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, Bibinagar-508126, Hyderabad, Telangana, India.
Seetu PaloDepartment of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bibinagar-508126, Hyderabad, Telangana, India.
Ashutosh RathDepartment of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bibinagar-508126, Hyderabad, Telangana, India.
Mishu ManglaDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, Bibinagar-508126, Hyderabad, Telangana, India.
Pooja RathodDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, Bibinagar-508126, Hyderabad, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMinimal serous uterine cancers (MUSCs) represent a distinct subset of endometrial malignancies characterized by early-stage presentation and unique histopathological features. These tumors typically manifest as intraepithelial or superficial serous carcinomas confined to endometrial polyps without myometrial invasion or lymphovascular involvement. MUSCs are predominantly diagnosed in postmenopausal women and are associated with favorable prognosis. CASE PRESENTATION: The present case report briefs the finding of a 60-year-old woman presenting to the gynecological outpatient department for a routine gynaecological check-up. She was a known case of type II diabetes mellitus, hypertension, and asthma. She had no history of postmenopausal bleeding or vaginal discharge. Incidentally, on per speculum examination, a polyp of 2x3 cm was seen protruding through the cervical opening (cervical os). Her transvaginal ultrasound revealed a postmenopausal uterus with a thickened endometrium of 10mm. Her histopathology report of dilatation and curettage with polypectomy revealed serous carcinoma against the background of atrophic endometrium. The patient was managed with staging laparotomy with Wertheim's hysterectomy with bilateral pelvic lymph node dissection, omentectomy, and parietal peritoneum biopsy. Her final histopathology report revealed Stage 1A1 MUSC with atrophic endometrium.

conclusionThe case report highlights the clinical significance of recognizing MUSC as an early- stage variant of endometrial cancer. Postmenopausal women, vulnerable to uterine serous carcinoma, require comprehensive sampling of all endometrial biopsies, curettings, and endometrial polyps to ensure early detection and accurate staging.

Indexed as

Cystadenocarcinoma, SerousEndometrial NeoplasmsPostmenopauseUterine NeoplasmsAsymptomatic DiseasesBiopsyFemaleHumansHysterectomyLymph Node ExcisionMiddle AgedNeoplasm StagingTreatment Outcomeendometrial cancerEndometrial polypestrogen receptorhistopathologyminimal uterine serous carcinomapelvic lymph nodes.postmenopausal womanuterine serous carcinoma

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.